Evidence map›Paper›PMID 27644326›Full record

ArticleMolecular and cellular biology2016

MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice.

Mei Jiang, Ana C Azevedo-Pouly, Tye G Deering, Chinh Q Hoang, Daniel DiRenzo, David A Hess, Stephen F Konieczny, Galvin H Swift, Raymond J MacDonald

Open access · bronzeAbstract read
In one paragraph

Article in Molecular and cellular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

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  20. MIST1, an Inductive Signal for Salivary Amylase in Mesenchymal Stem Cells.International journal of molecular sciences · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mei JiangDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Ana C Azevedo-PoulyDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Tye G DeeringDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Chinh Q HoangDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Daniel DiRenzoDepartment of Biological Sciences, Bindley Bioscience Center and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA.
David A HessDepartment of Biological Sciences, Bindley Bioscience Center and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA.
Stephen F KoniecznyDepartment of Biological Sciences, Bindley Bioscience Center and Purdue University Center for Cancer Research, Purdue University, West Lafayette, Indiana, USA.ORCID http://orcid.org/0000-0002-3281-3714
Galvin H SwiftDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Raymond J MacDonaldDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA raymond.macdonald@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-8576-766X
The University of Texas Southwestern Medical Center · USPurdue University West Lafayette · US

Funding

T32 Training Program in Mechanisms and Innovation in Vascular DiseaseT32HL098049 · NHLBI · STANFORD UNIVERSITY · PI Nicholas James Leeper, Philip S Tsao · 2010 to 2026
$6.3M
Transcriptional Regulators of the Exocrine Pancreatic PhenotypeR01DK061220 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI MACDONALD, RAYMOND J., MURTAUGH, LEWIS C · 2001 to 2019
$5.9M
Pancreas Transcription Factors and Disease Model SystemsR01DK055489 · NIDDK · PURDUE UNIVERSITY WEST LAFAYETTE · PI KONIECZNY, STEPHEN F · 2000 to 2017
$5.6M
Kras-Induced Cellular Plasticity in Pancreatic CancerR01CA124586 · NCI · PURDUE UNIVERSITY · PI KONIECZNY, STEPHEN F · 2008 to 2017
$3.1M
NCI NIH HHS R01 CA124586NHLBI NIH HHS T32 HL098049NIDDK NIH HHS R01 DK055489NIDDK NIH HHS R01 DK061220
6 · The paper itself

Abstract

Much remains unknown regarding the regulatory networks formed by transcription factors in mature, differentiated mammalian cells

Identifiers

PMID27644326
PMCPMC5108882
OpenAlexW2521982858

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.