Evidence map›Paper›PMID 27644129›Full record

ArticleMolecular neurobiology2017

Differentiation of Spermatogonia Stem Cells into Functional Mature Neurons Characterized with Differential Gene Expression.

Maryam Nazm Bojnordi, Hossein Azizi, Thomas Skutella, Mansoureh Movahedin, Fereshteh Pourabdolhossein, Amir Shojaei, Hatef Ghasemi Hamidabadi

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 31 citations in OpenAlex.

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  8. International journal of fertility & sterility · 2020
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  12. 2,4-D causes oxidative stress induction and apoptosis in human dental pulp stem cells (hDPSCs).Environmental science and pollution research international · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Maryam Nazm BojnordiDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. bojnordi@modares.ac.ir.
Hossein AziziDepartment of Biotechnology, Amol University of Special Modern Technologies, P.O. Box 4615863111, Amol, Iran.
Thomas SkutellaInstitute for Anatomy and Cell Biology, Medical Faculty, University of Heidelberg, Im Neuenheimer Feld 307, 69120, Heidelberg, Germany.
Mansoureh MovahedinDepartment of Anatomy, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran.
Fereshteh PourabdolhosseinNeuroscience Research Center, Babol University Medical of Sciences, Babol, Iran.
Amir ShojaeiDepartment of Physiology, Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran.
Hatef Ghasemi HamidabadiDepartment of Anatomy and Cell Biology, Faculty of Medicine, Mazandaran University of Medical Sciences, Sari, Iran. hatefdr@gmail.com.
Mazandaran University of Medical Sciences · IRTarbiat Modares University · IRAmol University of Special Modern Technologies · IRBabol University of Medical Sciences · IRHeidelberg University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Transplantation of embryonic stem cells (ESCs) is a promising therapeutic approach for the treatment of neurodegenerative diseases. However, ESCs are not usable clinically due to immunological and ethical limitations. The identification of an alternative safe cell source opens novel options via autologous transplantation in neuro-regeneration circumventing these problems. Here, we examined the neurogenic capacity of embryonic stem-like cells (ES-like cells) derived from the testis using neural growth factor inducers and utilized them to generate functional mature neurons. The neuronal differentiation of ES-like cells is induced in three stages. Stage 1 is related to embryoid body (EB) formation. To induce neuroprogenitor cells, EBs were cultured in the presence of retinoic acid, N

Indexed as

AnimalsCell DifferentiationCell LineCells, CulturedGene ExpressionMaleMiceMouse Embryonic Stem CellsNeurogenesisNeuronsSpermatogoniaTretinoinTretinoinDifferentiationEmbryonic stem cellsMature neuronsNeuroregenerative medicineSpermatogonia stem cells

Identifiers

PMID27644129
OpenAlexW2522753665

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.