Evidence map›Paper›PMID 27643726›Full record

Trial reportNutrition & diabetes2016

Improving diet, activity and wellness in adults at risk of diabetes: randomized controlled trial.

G Block, K M J Azar, R J Romanelli, T J Block, L P Palaniappan, M Dolginsky, C H Block

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrition & diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

G BlockTurnaround Health, Berkeley, CA, USA.ORCID 0000-0001-6722-930X
K M J AzarSutter Health Research, Development and Dissemination, Walnut Creek, CA, USA.
R J RomanelliPalo Alto Medical Foundation Research Institute, Palo Alto, CA, USA.
T J BlockTurnaround Health, Berkeley, CA, USA.
L P PalaniappanPalo Alto Medical Foundation Research Institute, Palo Alto, CA, USA.
M DolginskyPalo Alto Medical Foundation Research Institute, Palo Alto, CA, USA.
C H BlockTurnaround Health, Berkeley, CA, USA.
Palo Alto Institute · USSutter Health · US

Funding

Multi-Channel Automated Diet and Physical Activity Intervention for Pre-DiabeticsR44NR012617 · NINR · BERKELEY ANALYTICS, INC. · PI BLOCK, GLADYS · 2011 to 2014
$2.0M
META - Mentor, Educate, Train, Advocate: Patient Oriented Researchers in Cardiometabolic DiseaseK24HL150476 · NHLBI · STANFORD UNIVERSITY · PI Latha P Palaniappan · 2020 to 2026
$846k
NHLBI NIH HHS K24 HL150476NINR NIH HHS R44 NR012617
6 · The paper itself

Abstract

objectiveThe purpose of this analysis is to examine the effect of an algorithm-driven online diabetes prevention program on changes in eating habits, physical activity and wellness/productivity factors.

methodsThe intervention, Alive-PD, used small-step individually tailored goal setting and other features to promote changes in diet and physical activity. A 6-month randomized controlled trial was conducted among patients from a healthcare delivery system who had confirmed prediabetes (n =339). Change in weight and glycemic markers were measured in the clinic. Changes in physical activity, diet and wellness/productivity factors were self-reported. Mean age was 55 (s.d. 8.9) years, mean body mass index was 31 (s.d. 4.4) kg m(-2), 68% were white and 69% were male.

resultsThe intervention group increased fruit/vegetable consumption by 3.71 (95% confidence interval (CI) 2.73, 4.70) times per week (effect size 0.62), and decreased refined carbohydrates by 3.77 (95% CI 3.10, 4.44) times per week both significantly (P<0.001) greater changes than in the control group. The intervention group also reported a significantly greater increase in physical activity than in the control group, effect size 0.49, P<0.001. In addition, the intervention group reported a significant increase in self-rated health, in confidence in ability to make dietary changes and in ability to accomplish tasks, and a decrease in fatigue, compared with the control group. These changes paralleled the significant treatment effects on glycemic markers and weight.

conclusionsIn addition to promoting improvements in weight and glycemic markers, the Alive-PD program appears to improve eating habits and physical activity, behaviors important not just for diabetes prevention but for those with diagnosed diabetes or obesity. The improvements in wellness/productivity may derive from the diet and activity improvements, and from the satisfaction and self-efficacy of achieving goals.

Indexed as

Diet, HealthyExerciseBlood GlucoseBody Mass IndexDiabetes MellitusDietary CarbohydratesDietary FatsFeeding BehaviorFemaleFruitHealth BehaviorHealth PromotionHumansMaleMiddle AgedNutrition PolicyBlood GlucoseDietary CarbohydratesDietary Fats

Identifiers

PMID27643726
PMCPMC5048017
OpenAlexW2523131815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.