Evidence map›Paper›PMID 27643385›Full record

ArticleClinical and experimental immunology2017

RORγt antagonist suppresses M3 muscarinic acetylcholine receptor-induced Sjögren's syndrome-like sialadenitis.

M Tahara, H Tsuboi, S Segawa, H Asashima, M Iizuka-Koga, T Hirota, H Takahashi, Y Kondo, M Matsui, I Matsumoto and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Clinical and experimental immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Salivary gland immunizationFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2019
    Article
  6. Interferons and Dry Eye in Sjögren's Syndrome.International journal of molecular sciences · 2018
    Review
  7. Review
  8. Review
  9. T Helper 17 Cells in Primary Sjögren's Syndrome.Journal of clinical medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

M TaharaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
H TsuboiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
S SegawaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
H AsashimaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
M Iizuka-KogaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
T HirotaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
H TakahashiDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
Y KondoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
M MatsuiDepartment of Internal Medicine, Fureai Higashitotsuka Hospital, Yokohama, Kanagawa, Japan.
I MatsumotoDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
T SumidaDepartment of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki.
University of Tsukuba · JPFurukawa Electric (Japan) · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We showed recently that M3 muscarinic acetylcholine receptor (M3R)-reactive CD3

Indexed as

Adoptive TransferAminopyridinesAnimalsCells, CulturedDisease Models, AnimalEnzyme InhibitorsHumansMaleMiceMice, Inbred C57BLMice, KnockoutNuclear Receptor Subfamily 1, Group F, Member 3Peptide FragmentsReceptor, Muscarinic M3SialadenitisSjogren's SyndromeA213 compoundAminopyridinesEnzyme InhibitorsNuclear Receptor Subfamily 1, Group F, Member 3Peptide FragmentsReceptor, Muscarinic M3SulfonamidesM3 muscarinic acetylcholine receptorRORγt antagonistsialadenitisSjögren's syndrome

Identifiers

PMID27643385
PMCPMC5217906
OpenAlexW2521398235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.