Evidence map›Paper›PMID 27642630›Full record

ReviewSurgery research and practice2016

Role of Epidural Analgesia within an ERAS Program after Laparoscopic Colorectal Surgery: A Review and Meta-Analysis of Randomised Controlled Studies.

Giuseppe Borzellino, Nader Kamal Francis, Olivier Chapuis, Evguenia Krastinova, Valérie Dyevre, Michele Genna

2 registry-linked trialsOpen access · hybridAbstract readReview
In one paragraph

Review in Surgery research and practice, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03403842 naunknown statusnot on this mapstarted 2018, after this paper: background citation

Treatment of Acute Post-operative Pain in Patients Undergoing Laparoscopic Colon Resections

TypeinterventionalSponsorIRCCS San RaffaeleRan2018 to 2019Enrolled159ConditionsAnalgesiaArmsSublingual sufentanil tablet system, Peridural catheter, PCA Morphine
NCT05257941 phase1 / phase2terminatednot on this mapstarted 2022, after this paper: background citation

Randomized Prospective Study Comparison of Erector Spinae Plane Block and Intrathecal Opioid for Postoperative Analgesia After Laparoscopic Colorectal Surgery in an Enhanced Recovery Setting

TypeinterventionalSponsorIndiana UniversityRan2022 to 2024Enrolled116ConditionsSurgeryArmsIT Injection, ESP Block
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. [Enhanced recovery after surgery-Does the ERAS concept keep its promises].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2021
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  9. Epidurals in esophagectomy: end of an era?Journal of thoracic disease · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Giuseppe BorzellinoDepartment of Surgery, University Hospital of Verona, Piazzale A. Stefani 1, 37126 Verona, Italy.ORCID 0000-0002-3378-4548
Nader Kamal FrancisYeovil District Hospital and University of Bath, District Hospital NHS Foundation Trust, Taunton, UK.
Olivier ChapuisClinique Chirurgicale Val d'Or, Paris, France.
Evguenia KrastinovaClinical Research Platform, URC-CRC, Saint Antoine Hospital, APHP, Paris, France.ORCID 0000-0003-0230-3796
Valérie DyevreClinical Research Platform, URC-CRC, Saint Antoine Hospital, APHP, Paris, France.ORCID 0000-0003-3495-7225
Michele GennaDepartment of Surgery, University Hospital of Verona, Piazzale A. Stefani 1, 37126 Verona, Italy.ORCID 0000-0002-4984-6758
Sorbonne Université · FRUniversity of Verona · ITYeovil District Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction. Epidural analgesia has been a cornerstone of any ERAS program for open colorectal surgery. With the improvements in anesthetic and analgesic techniques as well as the introduction of the laparoscopy for colorectal resection, the role of epidural analgesia has been questioned. The aim of the review was to assess through a meta-analysis the impact of epidural analgesia compared to other analgesic techniques for colorectal laparoscopic surgery within an ERAS program. Methods. Literature research was performed on PubMed, Embase, and the Cochrane Library. All randomised clinical trials that reported data on hospital stay, postoperative complications, and readmissions rates within an ERAS program with and without an epidural analgesia after a colorectal laparoscopic resection were included. Results. Five randomised clinical trials were selected and a total of 168 patients submitted to epidural analgesia were compared to 163 patients treated by an alternative analgesic technique. Pooled data show a longer hospital stay in the epidural group with a mean difference of 1.07 (95% CI 0.06-2.08) without any significant differences in postoperative complications and readmissions rates. Conclusion. Epidural analgesia does not seem to offer any additional clinical benefits to patients undergoing laparoscopic colorectal surgery within an ERAS program.

Identifiers

PMID27642630
PMCPMC5013204
OpenAlexW2508314602

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.