ArticleAdvances in medicine2016
Antifungal Susceptibility Patterns of Candida Species Recovered from Endotracheal Tube in an Intensive Care Unit.
Article in Advances in medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- EnhancedCurrent medical mycology · 2023Article
- Description of the colonizing mycobiota of endotracheal tubes from patients admitted to two intensive care units in Bogotá, ColombiaBiomedica : revista del Instituto Nacional de Salud · 2023Article
- Antifungal Resistance of ClinicalIranian journal of public health · 2023Review
- Retrospective analysis on distribution and antifungal susceptibility profile ofFrontiers in public health · 2023Article
- Comparison of PCR-RFLP with 21-plex PCR and rDNA Sequencing for Identification of Clinical Yeast Isolates.Mycopathologia · 2021Article
- Antifungal susceptibility of non-albicansIranian journal of microbiology · 2019Article
- Implications of the presence of yeasts in tracheobronchial secretions of critically ill intubated patients.EXCLI journal · 2019Article
- Catheter-related candidemia and identification of causativeCurrent medical mycology · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
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Abstract
Aims. Biofilms formed by Candida species which associated with drastically enhanced resistance against most antimicrobial agents. The aim of this study was to identify and determine the antifungal susceptibility pattern of Candida species isolated from endotracheal tubes from ICU patients. Methods. One hundred forty ICU patients with tracheal tubes who were intubated and mechanically ventilated were surveyed for endotracheal tube biofilms. Samples were processed for quantitative microbial culture. Yeast isolates were identified to the species level based on morphological characteristics and their identity was confirmed by PCR-RFLP. Antifungal susceptibility testing was determined according to CLSI document (M27-A3). Results. Ninety-five strains of Candida were obtained from endotracheal tubes of which C. albicans (n = 34; 35.7%) was the most frequently isolated species followed by other species which included C. glabrata (n = 24; 25.2%), C. parapsilosis (n = 16; 16.8%), C. tropicalis (n = 12; 12.6%), and C. krusei (n = 9; 9.4%). The resulting MIC90 for all Candida species were in increasing order as follows: caspofungin (0.5 μg/mL); amphotericin B (2 μg/mL); voriconazole (8.8 μg/mL); itraconazole (16 μg/mL); and fluconazole (64 μg/mL). Conclusion. Candida species recovered from endotracheal tube are the most susceptible to caspofungin.
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Registered trials
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