Evidence map›Paper›PMID 27642491›Full record

ArticleThe Pan African medical journal2016

Acute flaccid paralysis surveillance indicators in the Democratic Republic of Congo during 2008-2014.

Hugo Kavunga Membo, Aaron Mweene, Serge Alain Sadeuh-Mba, Justin Masumu, Riziki Yogolelo, Norbert Ngendabanyikwa, Eddy Sokolua, Fred Sagamiko, Edgar Simulundu, Steve Ahuka and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Pan African medical journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hugo Kavunga MemboInstitut National de Recherche Biomédicale (INRB), P.O Box 1197 Kinshasa 1, Kinshasa, Democratic Republic of Congo; Department of Disease Control, School of Veterinary Medicine, University of Zambia, P.O Box 32379, Lusaka, Zambia.
Aaron MweeneDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, P.O Box 32379, Lusaka, Zambia.
Serge Alain Sadeuh-MbaService de Virologie, Centre Pasteur du Cameroun (CPC), rue Henri Dunant P.O Box 1274, Yaoundé, Cameroun.
Justin MasumuInstitut National de Recherche Biomédicale (INRB), P.O Box 1197 Kinshasa 1, Kinshasa, Democratic Republic of Congo.
Riziki YogoleloInstitut National de Recherche Biomédicale (INRB), P.O Box 1197 Kinshasa 1, Kinshasa, Democratic Republic of Congo.
Norbert NgendabanyikwaWorld Heath Organization (WHO), Central African Inter-country Bureau, Libreville, Gabon.
Eddy SokoluaWorld Heath Organization (WHO), Central African Inter-country Bureau, Libreville, Gabon.
Fred SagamikoDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, P.O Box 32379, Lusaka, Zambia.
Edgar SimulunduDepartment of Disease Control, School of Veterinary Medicine, University of Zambia, P.O Box 32379, Lusaka, Zambia.
Steve AhukaInstitut National de Recherche Biomédicale (INRB), P.O Box 1197 Kinshasa 1, Kinshasa, Democratic Republic of Congo.
Jean Jacques MuyembeInstitut National de Recherche Biomédicale (INRB), P.O Box 1197 Kinshasa 1, Kinshasa, Democratic Republic of Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe last wild poliovirus (WPV) case in Africa was reported in July 2014, thus underscoring the tremendous progress towards polio eradication worldwide. This study aimed to analyze the results of a seven-year surveillance of Acute Flaccid Paralysis (AFP) in the Democratic Republic of Congo (DRC) and to identify potential gaps that need to be addressed.

methodsEpidemiological and virological data obtained from AFP surveillance among AFP cases less than 15 years from January 2008 to December 2014 in DRC were retrospectively considered and analyzed in this study.

resultsOf the 13,749 AFP cases investigated, 58.9% received at least three doses of oral polio vaccine (OPV), 7.3% never received OPV, while the status of 18.3% was unknown. Analysis of surveillance performances showed that all, but two, indicators were below the required WHO-specified targets. Non-polio enterovirus (NPEV) isolation rate was consistently below the minimum requirement at ≥10% and the proportions of stool specimens that reached the laboratory within 72 hours of being sent were always below 15% (WHO target is ≥80%). Virus isolation and differentiation showed that 1.5% of AFP cases were infected by WPVs, 5.5% by Sabin strains, 0.5% by vaccine-derived polioviruses (VDPVs) and 7.2% by NPEVs.

conclusionOur findings indicate that additional efforts are needed to address the timeliness of adequate stool specimens' arrival to the laboratory. It remains essential to maintain high polio vaccine coverage and high AFP surveillance standards to ensure rapid detection and containment of either WPV importation or VDPV re-emergence in DRC.

Indexed as

Acute DiseaseChildChild, PreschoolDemocratic Republic of the CongoFecesFemaleHumansMaleParalysisPoliomyelitisPoliovirusPoliovirus Vaccine, OralPopulation SurveillanceRetrospective StudiesSpecimen HandlingTime FactorsPoliovirus Vaccine, OralDemocratic Republic of CongoindicatorsparalysisPoliomyelitispoliovirussurveillance

Identifiers

PMID27642491
PMCPMC5012780

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.