Evidence map›Paper›PMID 27641686›Full record

Trial reportJournal of the American Geriatrics Society2017

Depression and Anxiety Screens as Simultaneous Predictors of 10-Year Incidence of Diabetes Mellitus in Older Adults in Primary Care.

Tasneem Khambaty, Christopher M Callahan, Anthony J Perkins, Jesse C Stewart

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Clinical Trials.Gov: A Topical Analyses.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Tasneem KhambatyDepartment of Psychology, University of Miami, Coral Gables, Florida.
Christopher M CallahanCenter for Aging Research, Indiana University, Indianapolis, Indiana.
Anthony J PerkinsCenter for Aging Research, Indiana University, Indianapolis, Indiana.
Jesse C StewartDepartment of Psychology, Indiana University-Purdue University Indianapolis, Indianapolis, Indiana.
Regenstrief Institute · USIndiana University – Purdue University Indianapolis · USUniversity of Miami · US

Funding

BEHAVIORAL MEDICINE RESEARCH IN CARDIOVASCULAR DISEASET32HL007426 · NHLBI · UNIVERSITY OF MIAMI CORAL GABLES · PI PENEDO, FRANK J · 1985 to 2023
$7.1M
Patient-Oriented Research to Improve Geriatric Care-K24K24AG024078 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI CALLAHAN, CHRISTOPHER M · 2004 to 2013
$1.4M
MODELING ALZHEIMER DISEASE COSTS AND TRANSITIONSR01AG031222 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI CALLAHAN, CHRISTOPHER M · 2009 to 2010
$1.3M
NHLBI NIH HHS T32 HL007426NIA NIH HHS K24 AG024078NIA NIH HHS R01 AG031222
6 · The paper itself

Abstract

objectivesTo examine depression and anxiety screens and their individual items as simultaneous predictors of incident diabetes mellitus.

designTen-year follow-up study of individuals screened for the Improving Mood-Promoting Access to Collaborative Treatment (IMPACT) trial.

settingTwo large urban primary care clinics in Indianapolis, Indiana.

participantsDiverse sample (53% African American, 80% of lower socioeconomic status) of 2,156 older adults initially free of diabetes mellitus. MEASUREMENTS: Depression and anxiety screens were completed during routine primary care visits between 1999 and 2001. Incident diabetes mellitus data were obtained from an electronic medical record system and the Centers for Medicare and Medicaid Services analytical files though 2009.

resultsOver the 10-year period, 558 (25.9%) participants had diabetes mellitus onset. Cox proportional hazards models adjusted for demographic and diabetes mellitus risk factors revealed that a positive screen for anxiety, but not for depression, predicted incident diabetes mellitus when entered into separate models (anxiety: hazard ratio (HR) = 1.36, 95% confidence interval (CI) = 1.15-1.61, P < .001; depression: HR = 1.18, 95% CI = 0.95-1.46, P = .13) and when entered simultaneously into one model (anxiety: HR = 1.35, 95% CI = 1.12-1.61, P < .001; depression: HR = 1.04, 95% CI = 0.83-1.31, P = .73). The feeling anxious (P = .03) and the worry (P = .02) items predicted incident diabetes mellitus independent of the depression screen.

conclusionThese findings suggest that screening positive for anxiety is a risk factor for diabetes mellitus in older adults independent of depression and traditional diabetes mellitus risk factors. Anxiety requires greater consideration and awareness in the context of diabetes mellitus risk assessment and primary prevention.

Indexed as

AgedAnxietyDepressionDiabetes Mellitus, Type 2FemaleFollow-Up StudiesHumansIndianaMalePrimary Health CareProportional Hazards ModelsRisk FactorsUrban Populationanxietycomorbiditydepressiondiabetes mellitusprimary careprospective

Identifiers

PMID27641686
PMCPMC5311025
OpenAlexW2521492847

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.