ArticleEpidemiology and psychiatric sciences2017
Major depressive disorder is associated with subsequent adult-onset asthma: a population-based cohort study.
Article in Epidemiology and psychiatric sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Respiratory disease in people with major depressive disorder: A systematic review and Meta-analysis.European psychiatry : the journal of the Association of European Psychiatrists · 2025Pooled it
- The Association Between Depression and Survival in Asthma: The Mediating Role of Income.Depression and anxiety · 2026Article
- Care pathways, prescribing practices and treatment outcomes in major depressive disorder and treatment-resistant depression: retrospective, population-based cohort study.BJPsych open · 2024Article
- Research Trends and Hotspots on Asthma and Depression: A Bibliometric Analysis.Journal of asthma and allergy · 2024Review
- Coupling of spatial and directional functional network connectivity reveals a physiological basis for salience network hubs in asthma.Brain imaging and behavior · 2022Article
- Vascular Endothelial Growth Factor as a Putative Biomarker of Depression in Asthmatics with Reversible Airway Narrowing.Journal of clinical medicine · 2021Article
- Predicting Response to Group Cognitive Behavioral Therapy in Asthma by a Small Number of Abnormal Resting-State Functional Connections.Frontiers in neuroscience · 2020Article
- Evaluation of neuropsychiatric comorbidities and their clinical characteristics in Chinese children with asthma using the MINI kid tool.BMC pediatrics · 2019Article
- The role of gender and anxiety in the association between somatic diseases and depression: findings from three combined epidemiological studies in primary care.Epidemiology and psychiatric sciences · 2019Article
- The Prevalence of Chronic Physical Diseases Comorbid with Depression among Different Sex and Age Groups in South Korea: A Population-Based Study, 2007-2014.Psychiatry investigation · 2018Article
- Involvement of Innate and Adaptive Immune Systems Alterations in the Pathophysiology and Treatment of Depression.Frontiers in neuroscience · 2018Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo examine the incidence of asthma in adult patients with major depressive disorder (MDD).
methodsFrom the National Health Insurance database of Taiwan, we identified 30 169 adult patients who were newly diagnosed with MDD between 2000 and 2010. Individuals without depression were randomly selected four times and frequency matched for sex, age and year of diagnosis. Both cohorts were followed-up for the occurrence of asthma up to the end of 2011. Adjusted hazard ratios (aHRs) of asthma were estimated using the Cox proportional hazards method.
resultsThe overall incidence of asthma was 1.91-fold higher in the MDD cohort than in the non-depression cohort (7.55 v. 3.96 per 1000 person-years), with an aHR of 1.66 (95% confidence interval (CI) 1.55-1.78). In both cohorts, the incidence of asthma was higher in patients and controls who were female, aged, with comorbidities and users of aspirin or beta-adrenergic receptor blockers. No significant difference was observed in the occurrence of asthma between patients with MDD treated with selective serotonin reuptake inhibitors (SSRIs) and those treated with non-SSRIs (SSRIs to non-SSRIs aHR = 1.03, 95% CI 0.91-1.17).
conclusionAdult patients with MDD are at a higher risk of asthma than those without depression are.
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