Evidence map›Paper›PMID 27641543›Full record

SynthesisJournal of the American Geriatrics Society2017

Weight Loss Interventions in Older Adults with Obesity: A Systematic Review of Randomized Controlled Trials Since 2005.

John A Batsis, Lydia E Gill, Rebecca K Masutani, Anna M Adachi-Mejia, Heather B Blunt, Pamela J Bagley, Francisco Lopez-Jimenez, Stephen J Bartels

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in Journal of the American Geriatrics Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06933823 (Dietary Modification Intervention Involving Family Support), which is not on this map. Cited by 89 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
89citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06933823 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Dietary Modification Intervention Involving Family Support (FamNUTRI) for Managing Sarcopenic Obesity Among Community-dwelling Older Adults: a Pilot Randomized Controlled Trial

TypeinterventionalSponsorThe Hong Kong Polytechnic UniversityRan2025 to 2026Enrolled72ConditionsSarcopenic ObesityArmsDietary modification intervention involving family support, Dietary modification intervention
3 · Its place in the literature

Who cites it

89 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. EffectS of Lifestyle Interventions in Older PEople With Obesity (Effective SLOPE): a Systematic Review With Network Meta-Analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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  12. Application of the DJournal of cachexia, sarcopenia and muscle · 2023
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  18. Effect of Exercise Modality During Weight Loss on Bone Health in Older Adults With Obesity and Cardiovascular Disease or Metabolic Syndrome: A Randomized Controlled Trial.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018
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29 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

John A BatsisSection of General Internal Medicine, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.ORCID http://orcid.org/0000-0002-0845-4416
Lydia E GillDartmouth Centers for Health and Aging, Dartmouth College, New Hampshire.
Rebecca K MasutaniGeisel School of Medicine at Dartmouth, Dartmouth College, New Hampshire.
Anna M Adachi-MejiaGeisel School of Medicine at Dartmouth, Dartmouth College, New Hampshire.
Heather B BluntBiomedical Libraries, Dartmouth College, Hanover, New Hampshire.
Pamela J BagleyBiomedical Libraries, Dartmouth College, Hanover, New Hampshire.
Francisco Lopez-JimenezDivision of Cardiovascular Disease, Department of Medicine, Mayo Clinic, Rochester, Minnesota.
Stephen J BartelsGeisel School of Medicine at Dartmouth, Dartmouth College, New Hampshire.

Funding

Training Geriatric Mental Health Services ResearchersT32MH073553 · NIMH · DARTMOUTH-HITCHCOCK CLINIC · PI BRUCE, MARTHA L · 2005 to 2019
$6.4M
Health Promotion and Disease Prevention Research CenterU48DP005018 · DP · DARTMOUTH COLLEGE · PI ADACHI-MEJIA, ANNA MARIA · 2014 to 2018
$5.6M
RCT of a Learning Collaborative to Implement Health Promotion in Mental HealthR01MH102325 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BARTELS, STEPHEN J · 2014 to 2018
$3.7M
Self-Management Training and Automated Telehealth to Improve SMI Health OutcomesR01MH104555 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BARTELS, STEPHEN J · 2014 to 2018
$3.0M
Mobile Health Obesity Wellness Intervention in Rural Older Adults_Res1K23AG051681 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BATSIS, JOHN A. · 2016 to 2022
$1.1M
NCCDPHP CDC HHS U48 DP005018NIA NIH HHS K23 AG051681NIMH NIH HHS R01 MH102325NIMH NIH HHS R01 MH104555NIMH NIH HHS T32 MH073553
6 · The paper itself

Abstract

objectivesTo identify geriatric obesity interventions that can guide clinical recommendations.

designSystematic review using Medline (PubMed), Cochrane Central Register of Controlled Trials, Web of Science, CINAHL, EMBASE (Ovid), and PsycINFO (Proquest) from January 1, 2005, to October 12, 2015, to identify English-language randomized controlled trials.

participantsIndividuals aged 60 and older (mean age ≥65) and classified as having obesity (body mass index ≥30 kg/m

interventionsBehavioral weight loss interventions not involving pharmacological or procedural therapies lasting 6 months or longer. MEASUREMENTS: Two investigators performed the systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses criteria and achieved a high concordance rate (97.3%) in summarizing the primary outcomes. The three primary outcomes were weight loss, physical performance, and quality of life.

resultsOf 5,741 citations, 19 were included. (Six studies were unique, and the remaining 13 were based on the same study population.) Duration ranged from 6 to 18 months (n = 405 participants, age range 66.7-71.1). Weight loss in the intervention groups ranged from 0.5 to 10.7 kg (0.1-9.3%). Five studies had a resistance exercise program accompanying a dietary component. Greater weight loss was observed in groups with a dietary component than those with exercise alone. Exercise alone led to better physical function but no significant weight loss. Combined dietary and exercise components led to the greatest improvement in physical performance measures and quality of life and mitigated reductions in muscle and bone mass observed in diet-only study arms. Heterogeneous outcomes were observed, which limited the ability to synthesize the data quantitatively.

conclusionsThe evidence supporting geriatric obesity interventions to improve physical function and quality of life is of low to moderate quality. Well-designed trials are needed in this population.

Indexed as

Diet, ReducingExerciseWeight Reduction ProgramsBody Mass IndexHumansObesityQuality of LifeRandomized Controlled Trials as TopicWeight Lossinterventionsobesitysystematic reviewweight loss

Identifiers

PMID27641543
PMCPMC5414418

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.