Evidence map›Paper›PMID 27640081›Full record

ArticleDiagnostic microbiology and infectious disease2016

Comparison of molecular typing methods for the analyses of Acinetobacter baumannii from ICU patients.

J Kristie Johnson, Gwen L Robinson, LiCheng Zhao, Anthony D Harris, O Colin Stine, Kerri A Thom

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Diagnostic microbiology and infectious disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Molecular Typing and Resistance Profile ofAntibiotics (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Molecular epidemiology and antimicrobial resistance patterns of carbapenem-resistantFrontiers in cellular and infection microbiology · 2023
    Article
  5. Molecular Epidemiology of Clinical Carbapenem-ResistantTropical medicine and infectious disease · 2022
    Article
  6. Multidrug-ResistantLife (Basel, Switzerland) · 2021
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

J Kristie JohnsonDepartment of Pathology, University of Maryland School of Medicine Baltimore, MD; Epidemiology and Public Health, University of Maryland School of Medicine Baltimore, MD. Electronic address: jkjohnson@som.umaryland.edu.
Gwen L RobinsonDepartment of Pathology, University of Maryland School of Medicine Baltimore, MD.
LiCheng ZhaoDepartment of Pathology, University of Maryland School of Medicine Baltimore, MD.
Anthony D HarrisEpidemiology and Public Health, University of Maryland School of Medicine Baltimore, MD.
O Colin StineEpidemiology and Public Health, University of Maryland School of Medicine Baltimore, MD.
Kerri A ThomEpidemiology and Public Health, University of Maryland School of Medicine Baltimore, MD.

Funding

Epidemiology of imipenem-resistant P.aeruginosaR01AI060859 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI HARRIS, ANTHONY D · 2005 to 2013
$1.9M
K24 Clinical Research in Antimicrobial Resistance and Hospital EpidemiologyK24AI079040 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI HARRIS, ANTHONY D · 2009 to 2018
$1.8M
Epidemiology of Acinetobacter baumannii: An Emerging Nosocomial PathogenK23AI082450 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI THOM, KERRI · 2010 to 2014
$674k
NIAID NIH HHS K23 AI082450NIAID NIH HHS K24 AI079040NIAID NIH HHS R01 AI060859
6 · The paper itself

Abstract

Acinetobacter baumannii has emerged as an important cause of healthcare-associated infections causing great morbidity and mortality. Despite its clinical importance, it is still unknown which molecular typing method is the best to determine or confirm institutional outbreaks as well as to identify epidemiologically related isolates from different geographical areas. To determine the most discriminatory molecular typing method, we isolated A. baumannii from perianal swabs collected from intensive care unit (ICU) patients in a cohort study during 2002 and 2008. Strains from each year were analyzed by pulsed-field gel electrophoresis (PFGE), multi-locus sequence typing (MLST), and multi-locus variable-number tandem repeat analysis (MLVA). Genetic relatedness of the isolates was consistent between PFGE and MLST as well as between analyses of loci containing MLVA and MLST. Our data show that PFGE and MLVA are similar when discriminating between isolates and are both good methods to use when questioning whether two isolates are indistinguishable.

Indexed as

Disease OutbreaksAcinetobacter baumanniiAcinetobacter InfectionsCohort StudiesGenotypeHumansIntensive Care UnitsMolecular EpidemiologyMolecular TypingPerineumAcinetobacterMLSTMLVAPFGE

Identifiers

PMID27640081
PMCPMC6367931

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.