Evidence map›Paper›PMID 27640064›Full record

ReviewInternational urogynecology journal2017

Paravaginal defect: anatomy, clinical findings, and imaging.

Louise T S Arenholt, Bodil Ginnerup Pedersen, Karin Glavind, Marianne Glavind-Kristensen, John O L DeLancey

Registry-linked trialAbstract readReview
In one paragraph

Review in International urogynecology journal, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05602246 (Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS), which is not on this map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05602246 narecruitingnot on this mapstarted 2022, after this paper: background citation

Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS

TypeinterventionalSponsorCharles University, Czech RepublicRan2022 to 2034Enrolled592ConditionsPelvic Organ Prolapse, Cystocele, Cystocele and Incomplete Uterovaginal ProlapseArmsTransobturator cystocele repair, Anterior colporrhaphy
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Trans-obturator cystocele repair of level 2 paravaginal defect.International urogynecology journal · 2020
    Article
  18. Ultrasound imaging of the perineal body: a useful clinical tool.International urogynecology journal · 2020
    Observational
  19. Article
  20. Laparoscopic approach to pelvic organ prolapse - the way to go or a blind alley?Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Louise T S ArenholtCentre for Clinical Research, Department of Obstetrics and Gynecology, North Denmark Regional Hospital, Bispensgade 67, 9800, Hjorring, Denmark. LTSA@RN.DK.
Bodil Ginnerup PedersenDepartment of Radiology, Aarhus University Hospital, Skejby, Denmark.
Karin GlavindDepartment of Obstetrics and Gynecology, Aalborg University Hospital, Skejby, Denmark.
Marianne Glavind-KristensenDepartment of Obstetrics and Gynecology, Aalborg University Hospital, Skejby, Denmark.
John O L DeLanceyPelvic Floor Research Group, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.

Funding

Which pelvic floor defects cause stress incontinence?P50HD044406 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DELANCEY, JOHN O.L. · 2002 to 2017
$17.1M
Mechanisms of anterior vaginal wall support failureR01HD038665 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DELANCEY, JOHN O.L. · 2000 to 2014
$3.8M
NICHD NIH HHS P50 HD044406NICHD NIH HHS R01 HD038665
6 · The paper itself

Abstract

introduction and hypothesisThe paravaginal defect has been a topic of active discussion concerning what it is, how to diagnose it, its role in anterior vaginal wall prolapse, and if and how to repair it. The aim of this article was to review the existing literature on paravaginal defect and discuss its role in the anterior vaginal wall support system, with an emphasis on anatomy and imaging.

methodsArticles related to paravaginal defects were identified through a PubMed search ending 1 July 2015.

resultsSupport of the anterior vaginal wall is a complex system involving levator ani muscle, arcus tendineus fascia pelvis (ATFP), pubocervical fascia, and uterosacral/cardinal ligaments. Studies conclude that physical examination is inconsistent in detecting paravaginal defects. Ultrasound (US) and magnetic resonance imaging (MRI) have been used to describe patterns in the appearance of the vagina and bladder when a paravaginal defect is suspected. Different terms have been used (e.g., sagging of bladder base, loss of tenting), which all represent changes in pelvic floor support but that could be due to both paravaginal and levator ani defects.

conclusionParavaginal support plays a role in supporting the anterior vaginal wall, but we still do not know the degree to which it contributes to the development of prolapse. Both MRI and US are useful in the diagnosis of paravaginal defects, but further studies are needed to evaluate their use.

Indexed as

FemaleHumansMagnetic Resonance ImagingPelvic FloorPelvic Organ ProlapseUltrasonographyUrinary BladderVaginaAnatomyArcus tendineus fascia pelvisMRIParavaginal defectPelvic organ prolapseUltrasound

Identifiers

PMID27640064
PMCPMC5429977

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.