Evidence map›Paper›PMID 27639939›Full record

Trial reportThe Journal of allergy and clinical immunology2017

Heterogeneous inflammatory patterns in chronic rhinosinusitis without nasal polyps in Chicago, Illinois.

Bruce K Tan, Aiko I Klingler, Julie A Poposki, Whitney W Stevens, Anju T Peters, Lydia A Suh, James Norton, Roderick G Carter, Kathryn E Hulse, Kathleen E Harris and 7 more

Abstract readClinical TrialLetter
In one paragraph

Trial report in The Journal of allergy and clinical immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed.

  1. Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
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  13. Advancements and future directions in chronic rhinosinusitis: understanding inflammatory mechanisms (2000-2023).European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Review
  14. Clinical and mechanistic advancements in aspirin exacerbated respiratory disease.The Journal of allergy and clinical immunology · 2025
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Bruce K TanDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Aiko I KlinglerDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Julie A PoposkiDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Whitney W StevensDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Anju T PetersDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Lydia A SuhDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
James NortonDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Roderick G CarterDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Kathryn E HulseDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Kathleen E HarrisDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Leslie C GrammerDivision of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Robert P SchleimerDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Kevin C WelchDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Stephanie S SmithDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
David B ConleyDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Robert C KernDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Atsushi KatoDepartment of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, Ill; Division of Allergy-Immunology, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill. Electronic address: a-kato@northwestern.edu.

Funding

Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisU19AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KERN, ROBERT C · 2014 to 2017
$7.9M
Northwestern University Patient-centered Intervention and Engagement TrainingK12HS023011 · AHRQ · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CELLA, DAVID · 2014 to 2018
$3.7M
Glucocorticosteroid Action In Inflammatory DiseaseR37HL068546 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2009 to 2018
$3.5M
Role of Thymic Stromal Lymphopoietin in Chronic RhinosinusitisR01AI104733 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KATO, ATSUSHI · 2014 to 2018
$1.9M
Role for B-cell mediated olfactory loss in Chronic Sinusitis with Nasal PolypsK23DC012067 · NIDCD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI TAN, BRUCE K · 2012 to 2016
$1.1M
AHRQ HHS K12 HS023011NHLBI NIH HHS R37 HL068546NIAID NIH HHS R01 AI104733NIAID NIH HHS U19 AI106683NIDCD NIH HHS K23 DC012067
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdolescentAdultAgedChicagoChronic DiseaseFemaleHumansInflammationMaleMiddle AgedNasal PolypsRhinitisSinusitis

Identifiers

PMID27639939
PMCPMC5303134

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.