Evidence map›Paper›PMID 27639376›Full record

ArticleBMC musculoskeletal disorders2016

Prevalence of osteoporosis in the Italian population and main risk factors: results of BoneTour Campaign.

Loredana Cavalli, Andrea Guazzini, Luisella Cianferotti, Simone Parri, Tiziana Cavalli, Alessia Metozzi, Francesca Giusti, Caterina Fossi, Dennis M Black, Maria Luisa Brandi

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  7. Article
  8. Article
  9. Article
  10. Early Menopause and Risk of Fractures-A Preventable Gap.Iranian journal of public health · 2023
    Article
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  12. Article
  13. Fracture risk assessment in celiac disease: a registry-based cohort study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Loredana CavalliDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Andrea GuazziniDepartment of Education and Psychology and Center for the Study of Complex Dynamics, VirtHuLab, University of Florence, Florence, Italy.
Luisella CianferottiDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Simone ParriDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Tiziana CavalliDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Alessia MetozziDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Francesca GiustiDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Caterina FossiDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy.
Dennis M BlackDepartment of Epidemiology and Biostatistics, University of California, San Francisco, CA, USA.
Maria Luisa BrandiDepartment of Surgery and Translational Medicine, University of Florence, Viale Pieraccini, 6-50139, Florence, Italy. marialuisa.brandi@unifi.it.
University of Florence · ITUniversity of California, San Francisco · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBoneTour is a campaign conducted throughout the Italian territory for the assessment of Italian people bone status and for the prevention of osteoporosis.

methodsA total of 7305 sequential subjects of both sexes were screened, collecting clinical data through the FRAX™ questionnaire, and measuring heel bone stiffness by Quantitative Ultrasonography (QUS). The 10-year risk for hip and major osteoporotic fractures was calculated taking into account personal or family history of fragility fracture, smoking, alcohol abuse, rheumatoid arthritis, prolonged steroids assumption. Additional risk factors were evaluated, including early menopause, poor sunlight exposure, low dietary calcium intake, physical inactivity, number of pregnancies, months of lactation, tobacco cigarettes smoked per year, specific causes of secondary osteoporosis. Through a correlation study, the influence of each factor on the development of osteoporosis was analyzed.

resultsAs many as 18 % of women suffer from osteoporosis, as defined by QUS T-score. The calculation of FRAX™ confirmed the weight of the already known risk factors. The correlation study revealed the significance of some additional factors, such as hyperthyroidism, nephrolithiasis, Crohn disease, ulcerative colitis, celiac disease, poor sun exposure, and oophorectomy before age 50.

conclusionsThe high prevalence of secondary osteoporosis in the Italian population clearly indicates the importance of additional risk factors not yet included in the FRAX™ algorithm, for which preventive measures should be considered. Screening campaigns may allow both early diagnosis and access to treatment.

Indexed as

AgedCalcaneusFemaleHumansItalyMaleMass ScreeningMiddle AgedOsteoporosisPrevalenceRisk FactorsUltrasonographyEpidemiologyFractureFRAXOsteoporosisPreventionQUSRisk factors

Identifiers

PMID27639376
PMCPMC5027125
OpenAlexW2518927207

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.