ArticleInternational journal of epidemiology2017
Lung and stomach cancer associations with groundwater radon in North Carolina, USA.
Article in International journal of epidemiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Radon exposure and potential health effects other than lung cancer: a systematic review and meta-analysis.Frontiers in public health · 2024Pooled it
- Natural radioactivity in Brazil: a systematic review.Environmental science and pollution research international · 2020Pooled it
- Gastric cancer susceptibility mapping using GIS and machine learning in East Azerbaijan province, Iran.International journal of health geographics · 2026Article
- Residential radon exposure and incident myocardial infarction and stroke risks in the All of Us Research Program.BMC medicine · 2025Article
- High-resolution national radon maps based on massive indoor measurements in the United States.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Standardized Mortality Ratios (SMRs) and Radon Exposure Analysis for Lung Cancer and All-Cause Mortality in Locorotondo, Southern Italy.Medicina (Kaunas, Lithuania) · 2024Article
- An overview on the relationship between residential radon and lung cancer: what we know and future research.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023Review
- Radon exposure: a major cause of lung cancer in nonsmokers.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023Review
- Impacts of Indoor Radon on Health: A Comprehensive Review on Causes, Assessment and Remediation Strategies.International journal of environmental research and public health · 2022Review
- Residential radon exposure and cancer.Oncology reviews · 2022Article
- Pilot groundwater radon mapping and the assessment of health risk from heavy metals in drinking water of southwest, Nigeria.Heliyon · 2022Article
- Groundwater radon exposure and risk of lung cancer: A population-based study in Finland.Frontiers in oncology · 2022Article
- Environmental/Occupational Exposure to Radon and Non-Pulmonary Neoplasm Risk: A Review of Epidemiologic Evidence.International journal of environmental research and public health · 2021Review
- Residential Radon in Manizales, Colombia: Results of a Pilot Study.International journal of environmental research and public health · 2021Article
- Radiation-related health hazards to uranium miners.Environmental science and pollution research international · 2020Review
- An exploration of colorectal cancer incidence rates in North Dakota, USA, via structural equation modeling.International journal of colorectal disease · 2019Article
- County level incidence rates of chronic lymphocytic leukemia are associated with residential radon levels.Future oncology (London, England) · 2017Article
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Abstract
Background: The risk of indoor air radon for lung cancer is well studied, but the risks of groundwater radon for both lung and stomach cancer are much less studied, and with mixed results. Methods: Geomasked and geocoded stomach and lung cancer cases in North Carolina from 1999 to 2009 were obtained from the North Carolina Central Cancer Registry. Models for the association with groundwater radon and multiple confounders were implemented at two scales: (i) an ecological model estimating cancer incidence rates at the census tract level; and (ii) a case-only logistic model estimating the odds that individual cancer cases are members of local cancer clusters. Results: For the lung cancer incidence rate model, groundwater radon is associated with an incidence rate ratio of 1.03 [95% confidence interval (CI) = 1.01, 1.06] for every 100 Bq/l increase in census tract averaged concentration. For the cluster membership models, groundwater radon exposure results in an odds ratio for lung cancer of 1.13 (95% CI = 1.04, 1.23) and for stomach cancer of 1.24 (95% CI = 1.03, 1.49), which means groundwater radon, after controlling for multiple confounders and spatial auto-correlation, increases the odds that lung and stomach cancer cases are members of their respective cancer clusters. Conclusion: Our study provides epidemiological evidence of a positive association between groundwater radon exposure and lung cancer incidence rates. The cluster membership model results find groundwater radon increases the odds that both lung and stomach cancer cases occur within their respective cancer clusters. The results corroborate previous biokinetic and mortality studies that groundwater radon is associated with increased risk for lung and stomach cancer.
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