Evidence map›Paper›PMID 27639111›Full record

ArticleJournal of obstetric, gynecologic, and neonatal nursing : JOGNN

Anti-Müllerian Hormone Levels and Urinary Cortisol in Women With Chronic Abdominal Pain.

Theresa M Hardy, Donna O McCarthy, Nicolaas H Fourie, Wendy A Henderson

Open access · hybridAbstract read
In one paragraph

Article in Journal of obstetric, gynecologic, and neonatal nursing : JOGNN. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Theresa M Hardy
Donna O McCarthy
Nicolaas H Fourie
Wendy A Henderson

Funding

Symptom Distress Mechanisms in Digestive DisordersZIANR000018 · NINR · NATIONAL INSTITUTE OF NURSING RESEARCH · PI HENDERSON, WENDY · 2009 to 2019
$5.2M
Intramural NIH HHS Z99 NR999999Intramural NIH HHS ZIA NR000018
6 · The paper itself

Abstract

objectiveTo explore the association of hypothalamic-pituitary-adrenal activity with ovarian functioning in women with and without chronic abdominal pain (CAP). DESIGN AND

settingA secondary data analysis was performed with data from female participants in a natural history protocol at the National Institutes of Health.

participantsA total of 36 women (age range = 19-39 years, mean = 27.11 years) were included in the study.

methodsThis pilot study was conducted with a subset of participants enrolled in a natural history protocol conducted in the Hatfield Clinical Research Center at the National Institutes of Health. The parent study included participants with and without CAP who provided a 5-hour urine sample for determination of cortisol levels and serum samples for determination of circulating levels of cortisol, luteinizing hormone, and follicle-stimulating hormone. CAP was defined as presence or absence of chronic pain for at least 6 months and was determined via self-report.

resultsAnti-Müllerian hormone (AMH) concentrations declined significantly with age as expected. When AMH levels were dichotomized as normal or abnormal (defined as higher or lower than age-specific normative ranges, respectively), there were significant associations between abnormal AMH levels and CAP and urine cortisol levels. Participants with CAP or low urine cortisol levels were significantly more likely to have abnormal AMH levels.

conclusionResults suggest that chronic abdominal pain and hypothalamic-pituitary-adrenal dysregulation may be associated with abnormal AMH levels.

Indexed as

Abdominal PainAdultAnti-Mullerian HormoneFemaleFollicle Stimulating HormoneHumansHydrocortisonePilot ProjectsUnited StatesYoung AdultAnti-Mullerian HormoneFollicle Stimulating HormoneHydrocortisoneAMHchronic abdominal painovarian reservereproductive health

Identifiers

PMID27639111
PMCPMC5107147
OpenAlexW2518662351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.