ArticlePsychoneuroendocrinology2016
Dominance rank causally affects personality and glucocorticoid regulation in female rhesus macaques.
Article in Psychoneuroendocrinology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 54 citations in OpenAlex.
- Social hierarchy influences monkeys' risky decisions.Communications biology · 2026Article
- Adaptive immune responses to vaccination reflect social status at first exposure in female rhesus macaques.bioRxiv : the preprint server for biology · 2026Article
- Effects of Lifelong Low Social Status on Inflammatory Markers in Adult Female Macaques.Biomolecules · 2026Article
- Distinguishing neural ensembles in the infralimbic cortex that regulate stress vulnerability and coping behavior.Neurobiology of stress · 2025Article
- Personality Assessment of Synanthropic Rhesus Macaques: Implications and Challenges.American journal of primatology · 2025Article
- Differential effects of Mediterranean vs. Western diets on coronary atherosclerosis and peripheral artery transcriptomics.Frontiers in nutrition · 2025Article
- A female-biased gene expression signature of dominance in cooperatively breeding meerkats.Molecular ecology · 2024Article
- Consistent Individual Differences Drive Collective Movements in a Tibetan Macaque Group.Animals : an open access journal from MDPI · 2024Article
- Aggressiveness predicts dominance rank in greylag geese: mirror tests and agonistic interactions.Royal Society open science · 2024Article
- Immune cell composition varies by age, sex and exposure to social adversity in free-ranging Rhesus Macaques.GeroScience · 2024Article
- Gut microbiome is associated with personality traits of free-ranging Tibetan macaques (Frontiers in microbiology · 2024Article
- Sex differences in dominance relationships in Syrian hamsters.Physiology & behavior · 2023Article
- Re-wilding model organisms: Opportunities to test causal mechanisms in social determinants of health and aging.Neuroscience and biobehavioral reviews · 2023Review
- Does the primate face cue personality?Personality neuroscience · 2023Article
- Determination of dexamethasone dose for cortisol suppression in adult common marmosets (Callithrix jacchus).Journal of medical primatology · 2022Article
- Evolutionary Approaches in Aging Research.Cold Spring Harbor perspectives in medicine · 2022Review
- The relationship of maternal rank, 5-HTTLPR genotype, and MAOA-LPR genotype to temperament in infant rhesus monkeys (Macaca mulatta).American journal of primatology · 2022Article
- Agonism and grooming behaviour explain social status effects on physiology and gene regulation in rhesus macaques.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Distinct gene regulatory signatures of dominance rank and social bond strength in wild baboons.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Article
- Gonadal steroid hormone receptors in the medial amygdala contribute to experience-dependent changes in stress vulnerability.Psychoneuroendocrinology · 2021Article
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Authors and funding
6 authors at 4 institutions in 3 countries.
Funding
Abstract
Low social status is frequently associated with heightened exposure to social stressors and altered glucocorticoid regulation by the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, personality differences can affect how individuals behave in response to social conditions, and thus may aggravate or protect against the effects of low status on HPA function. Disentangling the relative importance of personality from the effects of the social environment on the HPA axis has been challenging, since social status can predict aspects of behavior, and both can remain stable across the lifespan. To do so here, we studied an animal model of social status and social behavior, the rhesus macaque (Macaca mulatta). We performed two sequential experimental manipulations of dominance rank (i.e., social status) in 45 adult females, allowing us to characterize personality and glucocorticoid regulation (based on sensitivity to the exogenous glucocorticoid dexamethasone) in each individual while she occupied two different dominance ranks. We identified two behavioral characteristics, termed 'social approachability' and 'boldness,' which were highly social status-dependent. Social approachability and a third dimension, anxiousness, were also associated with cortisol dynamics in low status females, suggesting that behavioral tendencies may sensitize individuals to the effects of low status on HPA axis function. Finally, we found that improvements in dominance rank increased dexamethasone-induced acute cortisol suppression and glucocorticoid negative feedback. Our findings indicate that social status causally affects both behavioral tendencies and glucocorticoid regulation, and that some behavioral tendencies also independently affect cortisol levels, beyond the effects of rank. Together, they highlight the importance of considering personality and social status together when investigating their effects on HPA axis function.
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