Evidence map›Paper›PMID 27638802›Full record

ArticleEnvironmental science and pollution research international2016

Inhibitory effects of tributyl phosphate on algal growth, photosynthesis, and fatty acid synthesis in the marine diatom Phaeodactylum tricornutum.

Hao Song, Xiaoji Fan, Guangfu Liu, Jiahui Xu, Xingxing Li, Yuzhu Tan, Haifeng Qian

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 19 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hao SongDepartment of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Xiaoji FanCollege of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Guangfu LiuDepartment of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Jiahui XuDepartment of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Xingxing LiDepartment of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Yuzhu TanDepartment of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China.
Haifeng QianCollege of Environment, Zhejiang University of Technology, Hangzhou, 310032, People's Republic of China. hfqian@zjut.edu.cn.
Zhejiang University of Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The widely used solvent extractant, tributyl phosphate (TBP), primarily used as a solvent for the conventional processing of nuclear fuel, has come under scrutiny recently due to concerns surrounding potential environmental contamination and toxicity. In this study, we found that, in Phaeodactylum tricornutum, administration of TBP severely inhibited algal cell growth by reducing photosynthetic efficiency and inducing oxidative stress. We further explored the effect of TBP by examining the gene expression of the photosynthetic electron transport chain and its contribution to reactive oxygen species (ROS) burst. Our data revealed that TBP affected both fatty acid content and profile by regulating the transcription of genes related to glycolysis, fatty acid biosynthesis, and β-oxidation. These results demonstrated that TBP did in fact trigger the synthesis of ROS, disrupting the subcellular membrane structure of this aquatic organism. Our study brings new insight into the fundamental mechanism of toxicity exerted by TBP on the marine alga P. tricornutum.

Indexed as

PhotosynthesisDiatomsFatty AcidsOrganophosphatesReactive Oxygen SpeciesFatty AcidsOrganophosphatesReactive Oxygen Speciestributyl phosphateElectron transfer chainsFatty acidGene transcriptPhaeodactylum tricornutumTributyl phosphate

Identifiers

PMID27638802
OpenAlexW2519301668

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.