Evidence map›Paper›PMID 27638717›Full record

ReviewChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2016

Pathogenesis of cerebral palsy through the prism of immune regulation of nervous tissue homeostasis: literature review.

Natalya Lisovska, Zholtay Daribayev, Yevgeny Lisovskyy, Kenzhe Kussainova, Lana Austin, Sholpan Bulekbayeva

Abstract readReview
PubMed Publisher
In one paragraph

Review in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
4.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The complex aetiology of cerebral palsy.Nature reviews. Neurology · 2018
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Natalya LisovskaRepublican Children's Rehabilitation Center, Turan str., 36, Astana, Kazakhstan, 010000. lisovska67@mail.ru.
Zholtay DaribayevRepublican Children's Rehabilitation Center, Turan str., 36, Astana, Kazakhstan, 010000.
Yevgeny LisovskyyRepublican Children's Rehabilitation Center, Turan str., 36, Astana, Kazakhstan, 010000.
Kenzhe KussainovaRepublican Children's Rehabilitation Center, Turan str., 36, Astana, Kazakhstan, 010000.
Lana AustinDepartment of Pediatrics, Parirenyatwa Group of hospitals, Harare, Zimbabwe.
Sholpan BulekbayevaRepublican Children's Rehabilitation Center, Turan str., 36, Astana, Kazakhstan, 010000.
Parirenyatwa Hospital · ZW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe cerebral palsy is highly actual issue of pediatrics, causing significant neurological disability. Though the great progress in the neuroscience has been recently achieved, the pathogenesis of cerebral palsy is still poorly understood.

methodsIn this work, we reviewed available experimental and clinical data concerning the role of immune cells in pathogenesis of cerebral palsy. Maintaining of homeostasis in nervous tissue and its transformation in case of periventricular leukomalacia were analyzed.

resultsThe reviewed data demonstrate involvement of immune regulatory cells in the formation of nervous tissue imbalance and chronicity of inborn brain damage. The supported opinion, that periventricular leukomalacia is not a static phenomenon, but developing process, encourages our optimism about the possibility of its correction.

conclusionsThe further studies of changes of the nervous and immune systems in cerebral palsy are needed to create fundamentally new directions of the specific therapy and individual schemes of rehabilitation.

Indexed as

Cerebral PalsyHomeostasisHumansLeukomalacia, PeriventricularNervous SystemCerebral palsyImmune cellsPeriventricular leukomalaciaTissue homeostasis

Identifiers

PMID27638717
OpenAlexW2519595203

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.