ArticleJournal of experimental botany2016
Ghd2, a CONSTANS-like gene, confers drought sensitivity through regulation of senescence in rice.
Article in Journal of experimental botany, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.
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62 citing papers in PubMed, 1 synthesis or guideline pooled it, 120 citations in OpenAlex.
- CCT domain-containing genes in cereal crops: flowering time and beyond.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2020Pooled it
- Molecular Crosstalk Between Flowering Time and Drought Adaptation in Cereal Crops.Plants (Basel, Switzerland) · 2026Review
- Crops exposed to extreme conditions: perspectives of gene editing to improve stress tolerance.Plant cell reports · 2026Review
- Multifaceted roles of BBX transcription factors: impacts on key agronomical traits and environmental resilience.The New phytologist · 2026Review
- Genome-wide identification and expression analysis of the CCT gene family reveals its function in regulating heading date in proso millet (Frontiers in plant science · 2026Article
- Genome-wide analysis of the CCT gene family in Liriodendron chinense highlights potential functions in light signaling and chlorophyll biosynthesis.BMC plant biology · 2025Article
- Natural variation of GNP2 enhances grain number to benefit rice yield.Nature communications · 2025Article
- Comprehensive Identification of Key Genes Responsible for Leaf Senescence of Rice (Plants (Basel, Switzerland) · 2025Article
- Genome-Wide Identification and Expression Analysis of theInternational journal of molecular sciences · 2025Article
- Enhancing drought resilience in crops: mechanistic approaches in the face of climate challenge.Plant molecular biology · 2025Review
- Genome-wide identification and characterization of the CCT gene family in Chinese cabbage (Brassica rapa) response to abiotic stress.BMC genomics · 2025Article
- The BBX family and their response to abiotic stress in ginger (Zingiber officinale Roscoe).BMC genomics · 2025Article
- Genome-wide identification and functional analysis of the longan CONSTANS (CO) family.BMC plant biology · 2025Article
- Function diversification of CONSTANS-like genes in Pyrus and regulatory mechanisms in response to different light quality.BMC plant biology · 2025Article
- Circadian clock regulation in soybean senescence: a transcriptome analysis of early and late senescence types.BMC genomics · 2025Article
- Genome-Wide Identification ofInternational journal of molecular sciences · 2025Article
- Genome-wide identification and characterization analysis ofFrontiers in plant science · 2025Article
- Genome-Wide Identification, Characterization and Expression Patterns of the DBB Transcription Factor Family Genes in Wheat.International journal of molecular sciences · 2024Article
- Article
- Genome-Wide Identification and Expression Analysis of the COL Gene Family inCurrent issues in molecular biology · 2024Article
2 more citing papers are in PubMed but not listed here.
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
CONSTANS (CO)-like genes have been intensively investigated for their roles in the regulation of photoperiodic flowering, but very limited information has been reported on their functions in other biological processes. Here, we found that a CO-like gene, Ghd2 (Grain number, plant height, and heading date2), which can increase the yield potential under normal growth condition just like its homologue Ghd7, is involved in the regulation of leaf senescence and drought resistance. Ghd2 is expressed mainly in the rice (Oryza sativa) leaf with the highest level detected at the grain-filling stage, and it is down-regulated by drought stress conditions. Overexpression of Ghd2 resulted in significantly reduced drought resistance, while its knockout mutant showed the opposite phenotype. The earlier senescence symptoms and the transcript up-regulation of many senescence-associated genes (SAGs) in Ghd2-overexpressing transgenic rice plants under drought stress conditions indicate that Ghd2 plays essential roles in accelerating drought-induced leaf senescence in rice. Moreover, developmental and dark-induced leaf senescence was accelerated in the Ghd2-overexpressing rice and delayed in the ghd2 mutant. Several SAGs were confirmed to be regulated by Ghd2 using a transient expression system in rice protoplasts. Ghd2 interacted with several regulatory proteins, including OsARID3, OsPURα, and three 14-3-3 proteins. OsARID3 and OsPURα showed expression patterns similar to Ghd2 in rice leaves, with the highest levels at the grain-filling stage, whereas OsARID3 and the 14-3-3 genes responded differently to drought stress conditions. These results indicate that Ghd2 functions as a regulator by integrating environmental signals with the senescence process into a developmental programme through interaction with different proteins.
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