ArticleTrends in immunology2016
Mitochondrial Antigen Presentation: A Vacuolar Path to Autoimmunity in Parkinson's Disease.
Article in Trends in immunology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 11 citations in OpenAlex.
- Unraveling the Role of Proteinopathies in Parasitic Infections.Biomedicines · 2025Review
- The mitochondrial stress signaling tunes immunity from a view of systemic tumor microenvironment and ecosystem.iScience · 2024Review
- Mechanism and role of mitophagy in the development of severe infection.Cell death discovery · 2024Review
- Extra-nuclear histones: origin, significance and perspectives.Molecular and cellular biochemistry · 2022Review
- Emerging views of mitophagy in immunity and autoimmune diseases.Autophagy · 2020Article
- Common Neurodegeneration-Associated Proteins Are Physiologically Expressed by Human B Lymphocytes and Are Interconnected via the Inflammation/Autophagy-Related Proteins TRAF6 and SQSTM1.Frontiers in immunology · 2019Article
- PINK1 import regulation; a fine system to convey mitochondrial stress to the cytosol.BMC biology · 2018Review
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Mitochondrial antigens can be presented by MHC molecules and initiate adaptive immune responses but the mechanisms of mitochondrial antigen presentation (MitAP) have remained mostly unknown. A recent study proposes a new model whereby MitAP is mediated by a vesicle transport pathway that is suppressed by the Parkinson's disease (PD) associated proteins PTEN-induced putative kinase 1 (PINK1) and Parkin. This discovery brings a new perspective on the link between mitochondrial dysfunction and autoimmunity in PD.
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Registered trials
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