Evidence map›Paper›PMID 27637887›Full record

ArticleTransboundary and emerging diseases2017

Identification of a Lineage D Betacoronavirus in Cave Nectar Bats (Eonycteris spelaea) in Singapore and an Overview of Lineage D Reservoir Ecology in SE Asian Bats.

I H Mendenhall, S Borthwick, E S Neves, D Low, M Linster, B Liang, M Skiles, J Jayakumar, H Han, V Gunalan and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Transboundary and emerging diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Cencurut virus: A novelOne health (Amsterdam, Netherlands) · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Bat-borne viruses in Africa: a critical review.Journal of zoology (London, England : 1987) · 2020
    Review
  10. Article
  11. Review
  12. Article
  13. Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 3 countries.

I H MendenhallProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.ORCID http://orcid.org/0000-0003-4250-6459
S BorthwickProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
E S NevesProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
D LowProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
M LinsterProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
B LiangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
M SkilesCollege of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
J JayakumarProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
H HanBioinformatics Institute, Agency for Science, Technology and Research, Singapore.
V GunalanBioinformatics Institute, Agency for Science, Technology and Research, Singapore.
B P Y-H LeeDurrell Institute of Conservation and Ecology, School of Anthropology and Conservation, University of Kent, Canterbury, UK.
K OkaharaProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
L-F WangProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
S Maurer-StrohBioinformatics Institute, Agency for Science, Technology and Research, Singapore.
Y C F SuProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
G J D SmithProgramme in Emerging Infectious Diseases, Duke-NUS Medical School, Singapore.
Duke-NUS Medical School · SGAgency for Science, Technology and Research · SGDuke University · USNational Parks Board · SGNorth Carolina State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronaviruses are a diverse group of viruses that infect mammals and birds. Bats are reservoirs for several different coronaviruses in the Alphacoronavirus and Betacoronavirus genera. They also appear to be the natural reservoir for the ancestral viruses that generated the severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus outbreaks. Here, we detected coronavirus sequences in next-generation sequence data created from Eonycteris spelaea faeces and urine. We also screened by PCR urine samples, faecal samples and rectal swabs collected from six species of bats in Singapore between 2011 and 2014, all of which were negative. The phylogenetic analysis indicates this novel strain is most closely related to lineage D Betacoronaviruses detected in a diverse range of bat species. This is the second time that coronaviruses have been detected in cave nectar bats, but the first coronavirus sequence data generated from this species. Bat species from which this group of coronaviruses has been detected are widely distributed across SE Asia, South Asia and Southern China. They overlap geographically, often share roosting sites and have been witnessed to forage on the same plant. The addition of sequence data from this group of viruses will allow us to better understand coronavirus evolution and host specificity.

Indexed as

Host-Pathogen InteractionsAnimalsBetacoronavirusBiological EvolutionChiropteraCoronavirus InfectionsDisease ReservoirsEcologyFecesFemaleHigh-Throughput Nucleotide SequencingMalePhylogenyReverse Transcriptase Polymerase Chain ReactionSingaporeSpatio-Temporal Analysisdisease ecologydistributionevolutionvirus diversity

Identifiers

PMID27637887
PMCPMC7159162
OpenAlexW2518714442

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.