Evidence map›Paper›PMID 27637718›Full record

Trial reportIntensive care medicine2016

The use of low-dose IV haloperidol is not associated with QTc prolongation: post hoc analysis of a randomized, placebo-controlled trial.

Matthew S Duprey, Nada Al-Qadheeb, Russel Roberts, Yoanna Skrobik, Greg Schumaker, John W Devlin

Abstract readLetterRandomized Controlled Trial
In one paragraph

Trial report in Intensive care medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. In Reply.Deutsches Arzteblatt international · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Influence of intravenous administration of the antipsychotic drug benperidol on the QT interval.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthew S DupreySchool of Pharmacy, Northeastern University, 360 Huntington Ave, TF R218, Boston, MA, 02115, USA.
Nada Al-QadheebDepartment of Critical Care, Hafer Albatin Central Hospital, Riyadh, Saudi Arabia.
Russel RobertsDepartment of Pharmacy, Massachusetts General Hospital, Boston, MA, USA.
Yoanna SkrobikDivision of Critical Care, McGill University Health Centre, Montreal, QC, Canada.
Greg SchumakerDivision of Pulmonary, Critical Care and Sleep Medicine, Tufts Medical Center, Boston, MA, USA.
John W DevlinSchool of Pharmacy, Northeastern University, 360 Huntington Ave, TF R218, Boston, MA, 02115, USA. j.devlin@neu.edu.

Funding

Preventing ICU Subsyndromal Delirium Conversion to Delirium with HaloperidolR15AG034915 · NIA · NORTHEASTERN UNIVERSITY · PI DEVLIN, JOHN W. · 2010 to 2010
$322k
NIA NIH HHS R15 AG034915
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedAntipsychotic AgentsDeliriumDose-Response Relationship, DrugDouble-Blind MethodHaloperidolHumansIntensive Care UnitsLong QT SyndromeMiddle AgedRespiration, ArtificialAntipsychotic AgentsHaloperidol

Identifiers

PMID27637718
PMCPMC6988840

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.