Evidence map›Paper›PMID 27637585›Full record

ReviewTrends in endocrinology and metabolism: TEM2016

Sarcolipin: A Key Thermogenic and Metabolic Regulator in Skeletal Muscle.

Meghna Pant, Naresh C Bal, Muthu Periasamy

Abstract readReview
In one paragraph

Review in Trends in endocrinology and metabolism: TEM, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 128 citations in OpenAlex.

  1. Using thermal preference to understand mouse thermal biology.American journal of physiology. Endocrinology and metabolism · 2026
    Article
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  6. HSAInternational journal of molecular sciences · 2025
    Article
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  8. SERCA blockade as a treatment strategy for obesity.European journal of applied physiology · 2025
    Review
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  11. Article
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  16. mTORC1 in energy expenditure: consequences for obesity.Nature reviews. Endocrinology · 2024
    Review
  17. Article
  18. Article
  19. Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Meghna PantDepartment of Physiology and Cell Biology, Ohio State University, Columbus, OH, USA.
Naresh C BalSanford Burnham Medical Research Institute at Lake Nona, Orlando, FL, USA; School of Biotechnology, KIIT University, Bhubaneswar, Odisha, India.
Muthu PeriasamyDepartment of Physiology and Cell Biology, Ohio State University, Columbus, OH, USA; Sanford Burnham Medical Research Institute at Lake Nona, Orlando, FL, USA. Electronic address: mperiasamy@spbdiscovery.org.
The Ohio State University · USSanford Burnham Prebys Medical Discovery Institute · US

Funding

RECRUITMENT OF SKELETAL MUSCLE BASED ON NON-SHIVERING THERMOGENESIS IN HEALTH AND DISEASER01DK098240 · NIDDK · UNIVERSITY OF CENTRAL FLORIDA · PI PERIASAMY, MUTHU · 2013 to 2017
$1.9M
Identification of enhancers of energy expenditure via SLN/SERCA interactionK01DK102772 · NIDDK · SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE · PI BAL, NARESH CHANDRA · 2015 to 2015
$123k
NIDDK NIH HHS K01 DK102772NIDDK NIH HHS R01 DK098240
6 · The paper itself

Abstract

Skeletal muscle constitutes ∼40% of body mass and has the capacity to play a major role as thermogenic, metabolic, and endocrine organ. In addition to shivering, muscle also contributes to nonshivering thermogenesis via futile sarcoplasmic/endoplasmic reticulum Ca

Indexed as

AnimalsHumansMuscle ProteinsMuscle, SkeletalProteolipidsSarcoplasmic Reticulum Calcium-Transporting ATPasesThermogenesisMuscle ProteinsProteolipidssarcolipinSarcoplasmic Reticulum Calcium-Transporting ATPasesmetabolismsarcolipinSERCAskeletal musclethermogenesis

Identifiers

PMID27637585
PMCPMC5424604
OpenAlexW2520543091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.