Evidence map›Paper›PMID 27637565›Full record

ReviewTrends in neurosciences2016

Homeostatic Plasticity of Subcellular Neuronal Structures: From Inputs to Outputs.

Winnie Wefelmeyer, Christopher J Puhl, Juan Burrone

Open access · hybridAbstract readReview
In one paragraph

Review in Trends in neurosciences, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 130 citations in OpenAlex.

  1. Article
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  9. Live imaging of excitable axonal microdomains in ankyrin-G-GFP mice.bioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Review
  12. Review
  13. Article
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  15. Article
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  17. Creation of Neuronal Ensembles and Cell-Specific Homeostatic Plasticity through Chronic Sparse Optogenetic Stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  18. Article
  19. Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Winnie WefelmeyerCentre for Developmental Neurobiology, King's College London, New Hunt's House, Guy's Hospital Campus, London, SE1 1UL, UK. Electronic address: winnie.wefelmeyer@kcl.ac.uk.
Christopher J PuhlCentre for Developmental Neurobiology, King's College London, New Hunt's House, Guy's Hospital Campus, London, SE1 1UL, UK.
Juan BurroneCentre for Developmental Neurobiology, King's College London, New Hunt's House, Guy's Hospital Campus, London, SE1 1UL, UK. Electronic address: juan.burrone@kcl.ac.uk.
King's College London · GBGuy's Hospital · GB

Funding

Medical Research Council MR/N026063/1
6 · The paper itself

Abstract

Neurons in the brain are highly plastic, allowing an organism to learn and adapt to its environment. However, this ongoing plasticity is also inherently unstable, potentially leading to aberrant levels of circuit activity. Homeostatic forms of plasticity are thought to provide a means of controlling neuronal activity by avoiding extremes and allowing network stability. Recent work has shown that many of these homeostatic modifications change the structure of subcellular neuronal compartments, ranging from changes to synaptic inputs at both excitatory and inhibitory compartments to modulation of neuronal output through changes at the axon initial segment (AIS) and presynaptic terminals. Here we review these different forms of structural plasticity in neurons and the effects they may have on network function.

Indexed as

AnimalsAxonsHomeostasisHumansNeuronal PlasticityNeuronsPyramidal CellsSynapsesaxon initial segmentdendritic spineshomeostatic plasticitypresynaptic terminalsstructural plasticity

Identifiers

PMID27637565
PMCPMC5236059
OpenAlexW2520172604

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.