Evidence map›Paper›PMID 27637453›Full record

ReviewBrain research bulletin2017

Clustered structural and functional plasticity of dendritic spines.

Ju Lu, Yi Zuo

Abstract readReview
In one paragraph

Review in Brain research bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Article
  2. Review
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  5. Review
  6. Article
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  11. Review
  12. Role of Lateral Inhibition on Visual Number Sense.Frontiers in computational neuroscience · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. The Subcortical-Allocortical- NeocorticalFrontiers in synaptic neuroscience · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ju LuDepartment of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA. Electronic address: jlu39@ucsc.edu.
Yi ZuoDepartment of Molecular, Cell and Developmental Biology, University of California Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA. Electronic address: yizuo@ucsc.edu.

Funding

Dynamics and molecular mechanism of synaptic connectivity change during learningR01MH104227 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2014 to 2018
$2.1M
Contribution of astrocytes to the Fragile X SyndromeR01MH109475 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2016 to 2020
$2.0M
Neurovascular Mechanisms of Time-Dependencies in Stroke RehabilitationR01NS078791 · NINDS · UNIVERSITY OF TEXAS AT AUSTIN · PI DUNN, ANDREW K, JONES, THERESA A · 2012 to 2016
$1.7M
Development of synaptic abnormality in fragile X miceR01MH094449 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2012 to 2015
$1.5M
Development of synaptic abnormality in fragile X miceR56MH094449 · NIMH · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI ZUO, YI · 2011 to 2011
$372k
NIMH NIH HHS R01 MH094449NIMH NIH HHS R01 MH104227NIMH NIH HHS R01 MH109475NIMH NIH HHS R56 MH094449NINDS NIH HHS R01 NS078791
6 · The paper itself

Abstract

The configuration of synaptic circuits underlies their ability to process and store information. Research on dendritic spines has revealed that their structural and functional alterations are clustered along the parent dendrite. Here we review the evidence supporting such notion of clustered synaptic plasticity, discuss its functional implications and possible contributing factors, and suggest potential strategies to deal with open challenges.

Indexed as

AnimalsDendritic SpinesHumansNeuronal PlasticityClustered plasticityDendritic spineNeural circuitStructural dynamicsSynapse

Identifiers

PMID27637453
PMCPMC5554072

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.