ArticleThe Journal of biological chemistry2016
Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle.
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Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
4.0field-weighted citation impact, top 6% of its field
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Who cites it
45 citing papers in PubMed, 66 citations in OpenAlex.
- Cardiac SR-Mitochondria Contacts-Impact on Cardiac Physiology and Mitochondrial Fitness.Cells · 2025Review
- Calmodulin enhancement of mitochondrial calcium uniporter function in isolated mitochondria.Cell calcium · 2025Article
- Mechano-energetic uncoupling in heart failure.Nature reviews. Cardiology · 2025Review
- A simulation study on the role of mitochondria-sarcoplasmic reticulum CaThe Journal of physiology · 2025Article
- Article
- Sarcoplasmic reticulum-mitochondria microdomains: hugging and kissing in the heart.American journal of physiology. Cell physiology · 2025Review
- Mitochondrial Calcium Regulation of Cardiac Metabolism in Health and Disease.Physiology (Bethesda, Md.) · 2024Review
- MICU1 and MICU2 control mitochondrial calcium signaling in the mammalian heart.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Myocardial transcriptomic analysis of diabetic patients with aortic stenosis: key role for mitochondrial calcium signaling.Cardiovascular diabetology · 2024Article
- Distinct Effects of Mitochondrial NaJournal of the American Heart Association · 2023Article
- Intracellular to Interorgan Mitochondrial Communication in Striated Muscle in Health and Disease.Endocrine reviews · 2023Review
- Enhanced Mitochondria-SR Tethering Triggers Adaptive Cardiac Muscle Remodeling.Circulation research · 2023Article
- IGF-1 boosts mitochondrial function by a CaFrontiers in physiology · 2023Article
- Sarcomere maturation: function acquisition, molecular mechanism, and interplay with other organelles.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Spatial and Functional Crosstalk between the Mitochondrial NaInternational journal of molecular sciences · 2022Article
- Mitochondrial calcium exchange in physiology and disease.Physiological reviews · 2022Review
- Targeting calcium-mediated inter-organellar crosstalk in cardiac diseases.Expert opinion on therapeutic targets · 2022Article
- Spatial arrangement of proteins in planar and curved membranes by PPM 3.0.Protein science : a publication of the Protein Society · 2022Article
- Mitochondrial Function and Reactive Oxygen/Nitrogen Species in Skeletal Muscle.Frontiers in cell and developmental biology · 2022Review
- CaPflugers Archiv : European journal of physiology · 2022Review
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Sergio De La FuenteFrom the MitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Celia Fernandez-Sanzthe Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, and.
Caitlin VailFrom the MitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Elorm J AgraFrom the MitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Kira Holmstromthe Center for Molecular Medicine, Laboratory of Molecular Biology, and.
Junhui Sunthe Systems Biology Center, Laboratory of Cardiac Physiology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892.
Jyotsna Mishrathe Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, and.
Dewight Williamsthe Penn EM Resource Laboratory, University of Pennsylvania, Philadelphia, Pennsylvania 19104.
Toren Finkelthe Center for Molecular Medicine, Laboratory of Molecular Biology, and.
Elizabeth Murphythe Systems Biology Center, Laboratory of Cardiac Physiology, NHLBI, National Institutes of Health, Bethesda, Maryland 20892.
Suresh K JosephFrom the MitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Shey-Shing Sheuthe Center for Translational Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, and.
György CsordásFrom the MitoCare Center for Mitochondrial Imaging Research and Diagnostics, Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, Gyorgy.Csordas@jefferson.edu.
Thomas Jefferson University · USNational Heart Lung and Blood Institute · USNational Institutes of Health · USUniversity of Pennsylvania · US
Funding
NHLBI Animal Program DivisionZIGHL006020 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CLARK, TANNIA · 2009 to 2025
$47.3MMechanisms of cardiac ischemia-reperfusion injury and cardioprotectionZIAHL002066 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI MURPHY, ELIZABETH · 2009 to 2025
$20.4MMitochondria-SR Tethering: Its Role in Cardiac Bioenergetics and Ca2+ DynamicsR01HL122124 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, SHEU, SHEY-SHING · 2014 to 2025
$4.0MStructural-functional zoning of the mitochondrion in cardiac Ca2+, ROS, and energetics regulationR01HL142864 · NHLBI · THOMAS JEFFERSON UNIVERSITY · PI CSORDAS, GYORGY, SHEU, SHEY-SHING · 2018 to 2021
$2.5MRedox Regulation of Intracellular Calcium SignalingR01DK103558 · NIDDK · THOMAS JEFFERSON UNIVERSITY · PI HAJNOCZKY, GYORGY, JOSEPH, SURESH K · 2015 to 2018
$1.4MNHLBI NIH HHS R01 HL122124NHLBI NIH HHS R01 HL142864NIDDK NIH HHS R01 DK103558
Abstract
Control of myocardial energetics by Ca
Indexed as
AnimalsCalciumCalcium ChannelsCalcium SignalingMaleMiceMice, Inbred C57BLMitochondria, HeartMitochondrial MembranesMyocardiumMyocytes, CardiacRatsRats, Sprague-DawleySarcoplasmic ReticulumCalciumCalcium ChannelsEmre protein, mousemitochondrial calcium uniportercalcium channelcalcium transportmicroscopic imagingmitochondrial transportsignaling
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.