ArticleeLife2016
Dissociated sequential activity and stimulus encoding in the dorsomedial striatum during spatial working memory.
Article in eLife, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
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Who cites it
63 citing papers in PubMed.
- Visuospatial working memory in Huntington's disease: behavioural and structural brain correlates.Journal of neurology, neurosurgery, and psychiatry · 2026Article
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- Neural circuit models for evidence accumulation through choice-selective sequences.Nature communications · 2026Article
- Temporal sequence geometry enables odor recognition and generalization.bioRxiv : the preprint server for biology · 2026Article
- Task-related activity in auditory cortex enhances sound representation.Science advances · 2025Article
- Network dynamics underlying activity-timescale differences between cortical regions.bioRxiv : the preprint server for biology · 2025Article
- Regulation of working memory switches from striatal dopamine D2-receptor to D1-receptor neurons under high cognitive load.PLoS biology · 2025Article
- Learning Temporal Relationships Between Symbols with Laplace Neural Manifolds.Computational brain & behavior · 2025Article
- Impact and Interrelationships of Striatal Proteins, EPHB2, OPRM1, and PER2 on Mild Cognitive Impairment.Molecular neurobiology · 2025Article
- Ramping cells in the rodent medial prefrontal cortex encode time to past and future events via real Laplace transform.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Neuronal activation sequences in lateral prefrontal cortex encode visuospatial working memory during virtual navigation.Nature communications · 2024Article
- Cognition-enhancing and cognition-impairing doses of psychostimulants exert opposing actions on frontostriatal neural coding of delay in working memory.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Time Cells in the Retrosplenial Cortex.bioRxiv : the preprint server for biology · 2024Article
- Article
- Ramping cells in rodent mPFC encode time to past and future events via real Laplace transform.bioRxiv : the preprint server for biology · 2024Article
- Neurocomputational Models of Interval Timing: Seeing the Forest for the Trees.Advances in experimental medicine and biology · 2024Review
- Temporal encoding in deep reinforcement learning agents.Scientific reports · 2023Article
- Striatum-projecting prefrontal cortex neurons support working memory maintenance.Nature communications · 2023Article
- The respective activation and silencing of striatal direct and indirect pathway neurons support behavior encoding.Nature communications · 2023Article
- Stress degrades working memory-related frontostriatal circuit function.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Several lines of evidence suggest that the striatum has an important role in spatial working memory. The neural dynamics in the striatum have been described in tasks with short delay periods (1-4 s), but remain largely uncharacterized for tasks with longer delay periods. We collected and analyzed single unit recordings from the dorsomedial striatum of rats performing a spatial working memory task with delays up to 10 s. We found that neurons were activated sequentially, with the sequences spanning the entire delay period. Surprisingly, this sequential activity was dissociated from stimulus encoding activity, which was present in the same neurons, but preferentially appeared towards the onset of the delay period. These observations contrast with descriptions of sequential dynamics during similar tasks in other brains areas, and clarify the contribution of the striatum to spatial working memory.
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