ArticlePloS one2016
Changes in Choroidal Structures in Eyes with Chronic Central Serous Chorioretinopathy after Half-Dose Photodynamic Therapy.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Choroidal binarization analysis: clinical application.International ophthalmology · 2019Pooled it
- Decrease in choroidal blood flow after half and one-third dose verteporfin photodynamic therapy for chronic central serous chorioretinopathy.BMC ophthalmology · 2021Trial
- Deep learning-based automated classification of choroidal layers in en face swept-source optical coherence tomography images.BMC ophthalmology · 2025Article
- Central and Peripheral Changes in Retinal Vein Occlusion and Fellow Eyes in Ultra-Widefield Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2024Article
- En-face optical coherence tomography hyperreflective foci of choriocapillaris in central serous chorioretinopathy.Scientific reports · 2023Article
- Changes in choroidal structure following intravitreal aflibercept therapy for retinal vein occlusion.The British journal of ophthalmology · 2021Observational
- Choroidal and Retinal Changes After Systemic Adrenaline and Photodynamic Therapy in Non-Human Primates.Investigative ophthalmology & visual science · 2021Article
- Changes in Choroidal Component Ratio and Circulation After Coffee Intake in Healthy Subjects.Investigative ophthalmology & visual science · 2021Article
- Morphological Changes and Prognostic Factors before and after Photodynamic Therapy for Central Serous Chorioretinopathy.Pharmaceuticals (Basel, Switzerland) · 2021Article
- Diagnosis of central serous chorioretinopathy by deep learning analysis of en face images of choroidal vasculature: A pilot study.PloS one · 2021Article
- Photodynamic Therapy with Verteporfin for Chronic Central Serous Chorioretinopathy: A Review of Data and Efficacy.Pharmaceuticals (Basel, Switzerland) · 2020Review
- Choroidal Structure after Half-Dose Photodynamic Therapy in Chronic Central Serous Chorioretinopathy.Journal of clinical medicine · 2020Article
- CORRELATIONS BETWEEN CHOROIDAL STRUCTURES AND VISUAL FUNCTIONS IN EYES WITH RETINITIS PIGMENTOSA.Retina (Philadelphia, Pa.) · 2019Article
- Comparing effects of photodynamic therapy in central serous chorioretinopathy: full-dose versus half-dose versus half-dose-half-fluence.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019Article
- Article
- Kago-Eye2 software for semi-automated segmentation of subfoveal choroid of optical coherence tomographic images.Japanese journal of ophthalmology · 2019Article
- Automated segmentation of en face choroidal images obtained by optical coherent tomography by machine learning.Japanese journal of ophthalmology · 2018Article
- Semi-automated software to measure luminal and stromal areas of choroid in optical coherence tomographic images.Japanese journal of ophthalmology · 2018Article
- Multimodal retinal imaging in central serous chorioretinopathy treated with oral eplerenone or photodynamic therapy.Eye (London, England) · 2018Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine the structural changes in the choroid after half-dose photodynamic therapy (hPDT) in eyes with chronic central serous chorioretinopathy (CSC).
methodsThis was a retrospective interventional study of 29 eyes of 29 patients who underwent hPDT for chronic CSC with serous retinal detachment (SRD) and were followed for ≥3 months. Enhanced depth imaging optical coherence tomographic (EDI-OCT) images of the subfoveal choroid were converted to binary images. The central choroidal thickness (CCT), the cross sectional subfoveal choroidal area, the hyporeflective and hyperreflective areas of the inner, outer, and whole choroid were determined at the baseline, and at 1, 3, and 12 months after the hPDT.
resultsThe SRDs were resolved in 26 (89.7%) eyes at 3 months after the hPDT. The mean CCT (P = 0.001), the total choroidal area (P = 0.001), and the hypo-reflective area (P = 0.003) of the whole choroid were significantly decreased from the baseline at 3 months. The hyperreflective area of whole choroid was not significantly changed during the study period (P = 0.083). The hyperreflective but not the hyporeflective area of the inner choroid was significantly decreased at 3 months (P = 0.001, P = 1.000, respectively). The hyporeflective but not the hyperreflective area of the outer choroid was significantly decreased at 3 months (P = 0.001, P = 1.000, respectively).
conclusionsThe hyperreflective area of the inner choroid and hyporeflective area of the outer choroid were significantly decreased after hPDT for chronic CSC. Because the hyperreflective and hyporeflective area correspond to the choroidal stroma and vessels, respectively, the decreased CCT and subfoveal choroidal area after hPDT may be attributed to a decrease in the exudative changes in the inner choroidal stroma and the reduction of the dilation of the outer choroidal vessels.
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