ArticleSleep2016
A Longitudinal Twin and Sibling Study of Associations between Insomnia and Depression Symptoms in Young Adults.
Article in Sleep, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Sleep disturbances in anorexia nervosa.European eating disorders review : the journal of the Eating Disorders Association · 2025Pooled it
- The Interplay Between Sleep and Mental Health: A Genetic Perspective.Biological psychiatry · 2025Review
- Mind at rest, mind at risk: A prospective population-based study of sleep and subsequent mental disorders.Sleep medicine: X · 2025Article
- Sub-types of insomnia in adolescents: Insights from a quantitative/molecular twin study.JCPP advances · 2023Article
- The brain structure and genetic mechanisms underlying the nonlinear association between sleep duration, cognition and mental health.Nature aging · 2022Article
- Polygenic risk scores for major psychiatric and neurodevelopmental disorders contribute to sleep disturbance in childhood: Adolescent Brain Cognitive Development (ABCD) Study.Translational psychiatry · 2021Article
- Associations Between Sleep Quality and Health Span: A Prospective Cohort Study Based on 328,850 UK Biobank Participants.Frontiers in genetics · 2021Article
- Article
- Longitudinal Study of Sleep and Internalizing Problems in Youth Treated for Pediatric Anxiety Disorders.Journal of abnormal child psychology · 2020Observational
- Sleep problems and depression among 237 023 community-dwelling adults in 46 low- and middle-income countries.Scientific reports · 2019Article
- Hypnotic drug risks of mortality, infection, depression, and cancer: but lack of benefit.F1000Research · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo estimate genetic and environmental influences on the associations between insomnia and depression symptoms concurrently and longitudinally.
methodsBehavioral genetic analyses were conducted on data from the British longitudinal G1219 twin/sibling study. One thousand five hundred fiftysix twins and siblings participated at Time 1 (mean age = 20.3 years, SD = 1.76). Eight hundred sixty-two participated at Time 2 (mean age = 25.2 years, SD = 1.73 years). Participants completed the Insomnia Symptoms Questionnaire and the Short Mood and Feelings Questionnaire to assess symptoms of insomnia and depression respectively.
resultsGenetic effects accounted for 33% to 41% of the variance of the phenotypes. The phenotypic correlations were moderate (r = 0.34 to r = 0.52). The genetic correlations between the variables were high (0.73-1.00). Genetic effects accounted for a substantial proportion of the associations between variables (50% to 90%). Non-shared environmental effects explained the rest of the variance and covariance of the traits.
conclusionsWhile genetic effects play a modest role in insomnia and depression symptoms separately, they appear to play a more central role in concurrent and longitudinal associations between these phenotypes. This should be acknowledged in theories explaining these common associations.
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