Evidence map›Paper›PMID 27634669›Full record

Trial reportContemporary clinical trials2016

Rationale and study design of a patient-centered intervention to improve health status in chronic heart failure: The Collaborative Care to Alleviate Symptoms and Adjust to Illness (CASA) randomized trial.

David B Bekelman, Larry A Allen, Jamie Peterson, Brack Hattler, Edward P Havranek, Diane L Fairclough, Connor F McBryde, Paula M Meek

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Contemporary clinical trials, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. mHealth education interventions in heart failure.The Cochrane database of systematic reviews · 2020
    Pooled it
  3. Disease management interventions for heart failure.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Article
  8. "Journal of palliative medicine · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

David B BekelmanDepartment of Veterans Affairs, Eastern Colorado Health Care System, Denver, CO, USA; Division of General Internal Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA. Electronic address: david.bekelman@va.gov.
Larry A AllenDivision of Cardiology, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
Jamie PetersonDepartment of Veterans Affairs, Eastern Colorado Health Care System, Denver, CO, USA.
Brack HattlerDepartment of Veterans Affairs, Eastern Colorado Health Care System, Denver, CO, USA; Division of Cardiology, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
Edward P HavranekDivision of Cardiology, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA; Denver Health and Hospital Authority, Denver, CO, USA.
Diane L FaircloughUniversity of Colorado School of Public Health, Anschutz Medical Campus, Aurora, CO, USA.
Connor F McBrydeDepartment of Veterans Affairs, Eastern Colorado Health Care System, Denver, CO, USA; Division of General Internal Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.
Paula M MeekCollege of Nursing, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA.
University of Colorado Anschutz Medical Campus · USVA Eastern Colorado Health Care System · USColorado School of Public Health · USDenver Health Medical Center · US

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
Improving Symptoms and Quality of Life in Advanced Chronic Heart FailureR01NR013422 · NINR · DENVER RESEARCH INSTITUTE · PI BEKELMAN, DAVID B. · 2011 to 2015
$1.4M
NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR002535NINR NIH HHS R01 NR013422
6 · The paper itself

Abstract

While contemporary heart failure management has led to some improvements in morbidity and mortality, patients continue to report poor health status (i.e., burdensome symptoms, impaired function, and poor quality of life). The Collaborative Care to Alleviate Symptoms and Adjust to Illness (CASA) trial is a NIH-funded, three-site, randomized clinical trial that examines the effect of the CASA intervention compared to usual care on the primary outcome of patient-reported health status at 6months in patients with heart failure and poor health status. The CASA intervention involves a nurse who works with patients to treat symptoms (e.g., shortness of breath, fatigue, pain) using disease-specific and palliative approaches, and a social worker who provides psychosocial care targeting depression and adjustment to illness. The intervention uses a collaborative care team model of health care delivery and is structured and primarily phone-based to enhance reproducibility and scalability. This article describes the rationale and design of the CASA trial, including several decision points: (1) how to design a patient-centered intervention to improve health status; (2) how to structure the intervention so that it is reproducible and scalable; and (3) how to systematically identify outpatients with heart failure most likely to need and benefit from the intervention. The results should provide valuable information to providers and health systems about the use of team care to manage symptoms and provide psychosocial care in chronic illness.

Indexed as

Health StatusChronic DiseaseDepressionDyspneaEmotional AdjustmentFatigueHeart FailureHumansNursesPain ManagementPalliative CarePatient-Centered CarePatient Reported Outcome MeasuresQuality of LifeSocial WorkersHeart failurePalliative carePatient-reported outcomePsychosocial careQuality of lifeRandomized clinical trial

Identifiers

PMID27634669
PMCPMC9440472
OpenAlexW2520533345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.