Evidence map›Paper›PMID 27634039›Full record

ArticleThe Journal of biological chemistry2016

Histone Deacetylase SIRT1 Controls Proliferation, Circadian Rhythm, and Lipid Metabolism during Liver Regeneration in Mice.

Marina Maria Bellet, Selma Masri, Giuseppe Astarita, Paolo Sassone-Corsi, Maria Agnese Della Fazia, Giuseppe Servillo

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 77 citations in OpenAlex.

  1. CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  11. The circadian clock and metabolic homeostasis: entangled networks.Cellular and molecular life sciences : CMLS · 2021
    Review
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  15. Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Marina Maria BelletFrom the Department of Experimental Medicine, University of Perugia, 06132 Perugia, Italy, marina_bellet@yahoo.com.
Selma MasriCenter for Epigenetics and Metabolism, Department of Biological Chemistry, University of California, Irvine, Irvine, California 92697.
Giuseppe AstaritaHealth Sciences, Waters Corporation, Milford, Massachusetts 01757, and.
Paolo Sassone-CorsiCenter for Epigenetics and Metabolism, Department of Biological Chemistry, University of California, Irvine, Irvine, California 92697.
Maria Agnese Della FaziaFrom the Department of Experimental Medicine, University of Perugia, 06132 Perugia, Italy.
Giuseppe ServilloFrom the Department of Experimental Medicine, University of Perugia, 06132 Perugia, Italy, giuseppe.servillo@unipg.it.
University of Perugia · ITUniversity of California, Irvine · USGeorgetown University · US

Funding

Univ.of Calif., Irvine Cancer Center Support GrantP30CA062203 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI Christine Hui · 1994 to 2026
$57.9M
NCI NIH HHS P30 CA062203
6 · The paper itself

Abstract

Liver regeneration offers a distinctive opportunity to study cell proliferation in vivo Mammalian silent information regulator 1 (SIRT1), a NAD

Indexed as

Cell CycleCell ProliferationLipid MetabolismLiver RegenerationAnimalsHumansLiverLiver DiseasesMiceMice, KnockoutSirtuin 1Sirtuin 1circadian rhythmclock geneG1/S cyclinlipid metabolismpartial hepatectomyproliferationsirtuin

Identifiers

PMID27634039
PMCPMC5087747
OpenAlexW2519876786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.