Evidence map›Paper›PMID 27634011›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2016

Lactobacillus acidophilus counteracts inhibition of NHE3 and DRA expression and alleviates diarrheal phenotype in mice infected with Citrobacter rodentium.

Anoop Kumar, Arivarasu N Anbazhagan, Hayley Coffing, Ishita Chatterjee, Shubha Priyamvada, Tarunmeet Gujral, Seema Saksena, Ravinder K Gill, Waddah A Alrefai, Alip Borthakur and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 52 citations in OpenAlex.

  1. Foods (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Inhibition of protein kinase C-α and activation of ezrin byAmerican journal of physiology. Endocrinology and metabolism · 2023
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Barley Leaf AmelioratesNutrients · 2022
    Article
  11. Review
  12. Article
  13. Treg Cells and Epigenetic Regulation.Advances in experimental medicine and biology · 2021
    Article
  14. Article
  15. Review
  16. Epithelial transport in digestive diseases: mice, monolayers, and mechanisms.American journal of physiology. Cell physiology · 2020
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Anoop KumarDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Arivarasu N AnbazhaganDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Hayley CoffingDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Ishita ChatterjeeDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Shubha PriyamvadaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Tarunmeet GujralDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Seema SaksenaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Ravinder K GillDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Waddah A AlrefaiDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
Alip BorthakurDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois alipb@uic.edu.ORCID 0000-0002-5792-1279
Pradeep K DudejaDivision of Gastroenterology and Hepatology, Department of Medicine, University of Illinois at Chicago and Jesse Brown VA Medical Center, Chicago, Illinois.
University of Illinois Chicago · US

Funding

Intestinal 5-HT Transporter: A novel therapeutic target for GI disordersR01DK098170 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI GILL, RAVINDER K · 2014 to 2022
$3.0M
Probiotics:Potential Therapeutic Roles in DiarrheaR01DK081858 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DUDEJA, PRADEEP K · 2008 to 2017
$2.5M
Regulation of Intestinal Bile Acid TransportR01DK071596 · NIDDK · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALREFAI, WADDAH A. · 2005 to 2014
$2.3M
Regulation of Intestinal Sodium Absorption in Health and DiseaseI01BX002867 · VA · JESSE BROWN VA MEDICAL CENTER · PI Seema Saksena · 2016 to 2026
–
BLRD VA I01 BX000152BLRD VA I01 BX002867BLRD VA IK6 BX005243NIDDK NIH HHS R01 DK071596NIDDK NIH HHS R01 DK081858NIDDK NIH HHS R01 DK098170
6 · The paper itself

Abstract

Impaired absorption of electrolytes is a hallmark of diarrhea associated with inflammation or enteric infections. Intestinal epithelial luminal membrane NHE3 (Na

Indexed as

Citrobacter rodentiumLactobacillus acidophilusAnimalsAntiportersColitisColonCytokinesDiarrheaEnterobacteriaceae InfectionsMicePhosphorylationProbioticsSodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersSulfate TransportersTreatment OutcomeAntiportersCytokinesSlc26a3 protein, mouseSlc9a3 protein, mouseSodium-Hydrogen Exchanger 3Sodium-Hydrogen ExchangersSulfate TransportersEPECinfectious colitisNaCl absorptionprobiotics

Identifiers

PMID27634011
PMCPMC5130543
OpenAlexW2519442386

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.