Trial reportTobacco control2016
Cigarette smoking and electronic cigarette vaping patterns as a function of e-cigarette flavourings.
Trial report in Tobacco control, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
52 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- The Role of Nicotine and Flavor in the Abuse Potential and Appeal of Electronic Cigarettes for Adult Current and Former Cigarette and Electronic Cigarette Users: A Systematic Review.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Pooled it
- Impact of non-menthol flavours in e-cigarettes on perceptions and use: an updated systematic review.BMJ open · 2019Pooled it
- An E-Liquid Flavor Wheel: A Shared Vocabulary Based on Systematically Reviewing E-Liquid Flavor Classifications in Literature.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Pooled it
- A systematic review of consumer preference for e-cigarette attributes: Flavor, nicotine strength, and type.PloS one · 2018Pooled it
- Effect on Tobacco Use and Subjective Measures of Including E-cigarettes in a Simulated Ban of Menthol in Combustible Cigarettes.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022Trial
- The effects of inhaled flavors on intravenous nicotine.Experimental and clinical psychopharmacology · 2021Trial
- Comparative Indoor Pollution from Glo, Iqos, and Juul, Using Traditional Combustion Cigarettes as Benchmark: Evidence from the Randomized SUR-VAPES AIR Trial.International journal of environmental research and public health · 2020Trial
- Biomarkers of Exposure Among "Dual Users" of Tobacco Cigarettes and Electronic Cigarettes in Canada.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2019Trial
- Vaping characteristics and expectancies are associated with smoking cessation propensity among dual users of combustible and electronic cigarettes.Addiction (Abingdon, England) · 2019Trial
- Product acceptance and cigarette reduction: Results from a Velo® pouch actual use study among United States adults who smoke.Preventive medicine reports · 2026Article
- Assessing the abuse liability of U.S. Food and Drug Administration-authorized electronic nicotine delivery systems: Impact of nicotine flux, flavor, and menthol cigarette smoking status.Experimental and clinical psychopharmacology · 2026Article
- Cannabis use across the menstrual cycle: The impact of negative affect and cannabis use motives.Addictive behaviors · 2025Article
- Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective.Expert review of clinical pharmacology · 2025Review
- Evaluating the human abuse potential of concurrent use of electronic cigarettes and low nicotine cigarettes among adults who smoke.Experimental and clinical psychopharmacology · 2025Article
- Effects of E-Cigs on Physiological Pathways and Proposed Therapeutic Intervention with Bixin.Biomedicines · 2024Review
- What types of e-liquid products were more likely to offer price promotions?Tobacco control · 2024Article
- Use patterns of flavored non-cigarette tobacco products among US adults, 2010-2019.Preventive medicine · 2024Article
- Development and initial psychometric properties of the Cannabidiol Outcome Expectancies Questionnaire (CBD-OEQ).Psychological assessment · 2022Article
- Preferred flavors and tobacco use patterns in adult dual users of cigarettes and ENDS.Addictive behaviors · 2022Observational
- Flavor science in the context of research on electronic cigarettes.Frontiers in neuroscience · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
introductionThe present study examined the influence of flavouring on the smoking and vaping behaviour of cigarette smokers asked to adopt e-cigarettes for a period of 6 weeks.
methodsParticipants were 88 current male and female smokers with no intention to stop smoking, but who agreed to substitute e-cigarettes for their current cigarettes. On intake, participants were administered tests of taste and smell for e-cigarettes flavoured with tobacco, menthol, cherry and chocolate, and were given a refillable e-cigarette of their preferred flavour or a control flavour. Participants completed daily logs of cigarette and e-cigarette use and were followed each week.
resultsAnalyses over days indicated that, during the 6-week e-cigarette period, cigarette smoking rates dropped from an average of about 16 to about 7 cigarettes/day. e-Cigarette flavour had a significant effect such that the largest drop in cigarette smoking occurred among those assigned menthol e-cigarettes, and the smallest drop in smoking occurred among those assigned chocolate and cherry flavours. e-Cigarette vaping rates also differed significantly by flavour assigned, with the highest vaping rates for tobacco- and cherry-flavoured e-cigarettes, and the lowest rates for those assigned to chocolate.
conclusionsThe findings suggest that adoption of e-cigarettes in smokers may influence smoking rates and that e-cigarette flavourings can moderate this effect. e-Cigarette vaping rates are also influenced by flavourings. These findings may have implications for the utility of e-cigarettes as a nicotine replacement device and for the regulation of flavourings in e-cigarettes for harm reduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.