Evidence map›Paper›PMID 27633738›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2016

Modeling the detailed kinetics of mitochondrial cytochrome c oxidase: Catalytic mechanism and nitric oxide inhibition.

Venkat R Pannala, Amadou K S Camara, Ranjan K Dash

Open access · bronzeAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Engineering a highly selective, hemoprotein-based scavenger as a carbon monoxide poisoning antidote with no hypertensive effect.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  4. Review
  5. Revisiting reactive oxygen species production in hypoxia.Pflugers Archiv : European journal of physiology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Computational Modeling and Imaging of the Intracellular Oxygen Gradient.International journal of molecular sciences · 2022
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. NO control of mitochondrial function in normal and transformed cells.Biochimica et biophysica acta. Bioenergetics · 2017
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Venkat R PannalaDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Amadou K S CamaraDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin.
Ranjan K DashDepartment of Physiology, Medical College of Wisconsin, Milwaukee, Wisconsin; rdash@mcw.edu.
Medical College of Wisconsin · US

Funding

Stem Cell CoreP01GM066730 · NIGMS · MEDICAL COLLEGE OF WISCONSIN · PI DASH, RANJAN K · 2003 to 2019
$23.6M
Analyzing the Cardiac Power Grid: Adaptive responses to fluctuating local demandU01HL122199 · NHLBI · UNIVERSITY OF WASHINGTON · PI BEARD, DANIEL A, DASH, RANJAN K · 2015 to 2019
$3.3M
NHLBI NIH HHS U01 HL122199NIGMS NIH HHS P01 GM066730
6 · The paper itself

Abstract

Cytochrome c oxidase (CcO) catalyzes the exothermic reduction of O

Indexed as

CatalysisCell RespirationElectron TransportElectron Transport Complex IVHydrogen-Ion ConcentrationKineticsMitochondriaModels, BiologicalNitric OxideOxidation-ReductionOxidative PhosphorylationOxygenProtonsThermodynamicsElectron Transport Complex IVNitric OxideOxygenProtonshalf-saturation constantkinetic modelingoxygen reductionproton pumping

Identifiers

PMID27633738
PMCPMC5142251
OpenAlexW2520093652

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.