ArticleJournal of the American Heart Association2016
Sex Differences in Survival From Out-of-Hospital Cardiac Arrest in the Era of Regionalized Systems and Advanced Post-Resuscitation Care.
Article in Journal of the American Heart Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Gender differences and survival after an out-of-hospital cardiac arrest: a systematic review and meta-analysis.Internal and emergency medicine · 2021Pooled it
- Sex differences in survival after out-of-hospital cardiac arrest: a meta-analysis.Critical care (London, England) · 2020Pooled it
- Circulating Levels of miR-574-5p Are Associated with Neurological Outcome after Cardiac Arrest in Women: A Target Temperature Management (TTM) Trial Substudy.Disease markers · 2019Trial
- Sex differences in management and outcomes after out-of-hospital cardiac arrest with angiographically confirmed obstructive coronary artery disease.Resuscitation plus · 2026Article
- Coronary angiography and reperfusion therapy following out-of-hospital cardiac arrest in women.Resuscitation plus · 2026Article
- Article
- Association Between the Duration of Elevated Perfusion Pressure and Neurological Outcomes in Out-of-Hospital Cardiac Arrest Survivors.Reviews in cardiovascular medicine · 2025Article
- Sex Differences in In-Hospital Mortality Among Patients Receiving Veno-Arterial Extracorporeal Membrane Oxygenation and Extracorporeal Cardiopulmonary Resuscitation: A Propensity Score-Matched Analysis.Journal of the American Heart Association · 2025Article
- Comparative Efficacy of Extracorporeal Versus Conventional Cardiopulmonary Resuscitation in Adult Refractory Out-of-Hospital Cardiac Arrest: A Retrospective Study at a Single Center.Journal of clinical medicine · 2025Article
- Gender disparities in out-of-hospital cardiac arrest: implications for public health and bystander interventions in Zhengzhou.Frontiers in medicine · 2025Article
- The Role of Sex and Gender in Precision Emergency Medicine: A Scoping Review and Proposed Hierarchy.Clinical therapeutics · 2024Article
- Social determinants and pre-arrest care patterns associated with cardiac arrest and mortality.Resuscitation · 2024Article
- Epidemiology and outcome of out-of-hospital cardiac arrest in Salt Lake City: Sex-based investigations.Journal of the American College of Emergency Physicians open · 2024Article
- Frequency of resuscitation attempts with dying nursing home residents. A full survey in an urban district in Germany based on registry data from 2018-2021.Resuscitation plus · 2023Article
- Sex- and Age-Based Disparities in Public Access Defibrillation, Bystander Cardiopulmonary Resuscitation, and Neurological Outcome in Cardiac Arrest.JAMA network open · 2023Article
- Association between sex and survival after out-of-hospital cardiac arrest: A systematic review and meta-analysis.Journal of the American College of Emergency Physicians open · 2023Article
- Association Between Postresuscitation 12-Lead ECG Features and Early Mortality After Out-of-Hospital Cardiac Arrest: A Post Hoc Subanalysis of the PEACE Study.Journal of the American Heart Association · 2023Article
- Association of sex with post-arrest care and outcomes after out-of-hospital cardiac arrest of initial shockable rhythm: a nationwide cohort study.Frontiers in cardiovascular medicine · 2023Article
- Sex-Based Differences in 30-Day Readmissions After Cardiac Arrest: Analysis of the Nationwide Readmissions Database.Journal of the American Heart Association · 2022Article
- The association between CPR quality of In-hospital resuscitation and sex: A hypothesis generating, prospective observational study.Resuscitation plus · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe purpose of this study was to evaluate sex differences in out-of-hospital cardiac arrest (OHCA) characteristics, interventions, and outcomes. METHODS AND
resultsThis is a retrospective analysis from a regionalized cardiac arrest system. Data on patients treated for OHCA are reported to a single registry, from which all adult patients were identified from 2011 through 2014. Characteristics, treatment, and outcomes were evaluated with stratification by sex. The adjusted odds ratio (OR) for survival with good neurological outcome (cerebral performance category 1 or 2) was calculated for women compared to men. There were 5174 out-of-hospital cardiac arrests (OHCAs; 3080 males and 2094 females). Women were older, median 71 (interquartile range [IQR], 59-82) versus 66 years (IQR, 55-78). Despite similar frequency of witnessed arrest, women were less likely to present with a shockable rhythm (22% vs 35%; risk difference [RD], 13%; 95% CI, 11-15), have ST-segment elevation myocardial infarction (23% vs 32%; RD, 13%; 95% CI, 7-11), or receive coronary angiography (11% vs 25%; RD, 14%; 95% CI, 12-16), percutaneous coronary intervention (5% vs 14%; RD, 9%; 95% CI, 7-11), or targeted temperature management (33% vs 40%; RD, 7%; 95% CI, 4-10). Women had decreased survival to discharge (33% vs 40%; RD, 7%; 95% CI, 4-10) and a lower proportion of good neurological outcome (16% vs 24%; RD, 8%; 95% CI, 6-10). In multivariable modeling, female sex was not associated with decreased survival with good neurological outcome (OR, 0.9; 95% CI, 0.8-1.1).
conclusionsSex-related differences in OHCA characteristics and treatment are predictors of survival outcome disparities. With adjustment for these factors, sex was not associated with survival or neurological outcome after OHCA.
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