ArticleApplied microbiology and biotechnology2016
Development of putative probiotics as feed additives: validation in a porcine-specific gastrointestinal tract model.
Article in Applied microbiology and biotechnology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- In Vitro Phenotypic Screening and MALDI-TOF Identification of Lactic Acid Bacteria Isolated from Feces of Suckling Piglets with Antibacterial Activity.Animals : an open access journal from MDPI · 2026Article
- A probiotic Brevibacillus laterosporus promotes chicken growth performance immunity and gut health.Scientific reports · 2025Article
- Probiotic bacteria of wild boar origin intended for piglets - AnVeterinarni medicina · 2024Article
- Impact of Long-Term Supplementation with Probiotics on Gut Microbiota and Growth Performance in Post-Weaned Piglets.Animals : an open access journal from MDPI · 2024Article
- Whole-genome sequencing of Pseudoalteromonas piscicida 2515 revealed its antibacterial potency against Vibrio anguillarum: a preliminary invitro study.Antonie van Leeuwenhoek · 2024Article
- Characterization of feline-originated probiotics Lactobacillus rhamnosus CACC612 and Bifidobacterium animalis subsp. lactis CACC789 and and evaluation of their host response.BMC veterinary research · 2024Article
- In Vitro Human Gastrointestinal Tract Simulation Systems: A Panoramic Review.Probiotics and antimicrobial proteins · 2024Review
- Article
- Probiotic potential of Saccharomyces cerevisiae GILA with alleviating intestinal inflammation in a dextran sulfate sodium induced colitis mouse model.Scientific reports · 2023Article
- Maternal amoxicillin affects piglets colon microbiota: microbial ecology and metabolomics in a gut model.Applied microbiology and biotechnology · 2022Article
- Perspectives and advances in probiotics and the gut microbiome in companion animals.Journal of animal science and technology · 2022Review
- Article
- Protective Action ofMaterials (Basel, Switzerland) · 2021Article
- Effects of Lactobacillus salivarius isolated from feces of fast-growing pigs on intestinal microbiota and morphology of suckling piglets.Scientific reports · 2021Article
- The Influence of Diet on Oxidative Stress and Inflammation Induced by Bacterial Biofilms in the Human Oral Cavity.Materials (Basel, Switzerland) · 2021Review
- Impact of the Diet on the Formation of Oxidative Stress and Inflammation Induced by Bacterial Biofilm in the Oral Cavity.Materials (Basel, Switzerland) · 2021Article
- Mycotoxin Removal byToxins · 2021Article
- Article
- Alterations of Suckling Piglet Jejunal Microbiota Due to Infection With Porcine Epidemic Diarrhea Virus and Protection Against Infection byFrontiers in veterinary science · 2021Article
- Aggrandizement of fermented cucumber through the action of autochthonous probiotic cum starter strains ofAnnals of microbiology · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Enforced restrictions on the use of antibiotics as growth promoters (AGPs) in animal production have prompted investigations into alternative feed additives in recent decades. Probiotics are currently the main feed additive used in livestock. However, the selection of probiotic candidates relies on human-based methods and little is known about the verification criteria for host-specific selection. We investigated the probiotic potential of Lactobacillus salivarius strains isolated from fed pig feces for their use as porcine feed additives. Two methods were developed that simulated the pig gastrointestinal (GI) tract and the intestinal epithelium, and these were compared with human-based in vitro methods and used for selecting porcine probiotics. Lactobacillus salivarius strain LS6 was identified as a promising probiotic strain for potential use as a porcine feed additive. This strain prevented disruption of the epithelial integrity of pig small intestine (PSI) cells by inhibiting the adherence of enterotoxigenic Escherichia coli K88. It also showed high survival rates in the in vitro pig GI tract model and good adhesion to PSI cells. We propose that host target-specific screening and validation methods are important tools in the development of effective probiotic feed additives, and this approach may support future-oriented agriculture.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.