Evidence map›Paper›PMID 27632579›Full record

ArticlePloS one2016

MetaStorm: A Public Resource for Customizable Metagenomics Annotation.

Gustavo Arango-Argoty, Gargi Singh, Lenwood S Heath, Amy Pruden, Weidong Xiao, Liqing Zhang

Abstract read
In one paragraph

Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gustavo Arango-ArgotyDepartment of Computer Science, Virginia Tech, Blacksburg, Virginia, United States of America.
Gargi SinghDepartment of Civil Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, India.
Lenwood S HeathDepartment of Computer Science, Virginia Tech, Blacksburg, Virginia, United States of America.
Amy PrudenDepartment of Civil and Environmental Engineering, Virginia Tech, Blacksburg, Virginia, United States of America.
Weidong XiaoDepartment of Microbiology and Immunology, Temple University School of Medicine, Philadelphia, United States of America.
Liqing ZhangDepartment of Computer Science, Virginia Tech, Blacksburg, Virginia, United States of America.

Funding

Molecular Biology of Recombinant AAV GenomesR01HL080789 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI XIAO, WEIDONG · 2006 to 2014
$3.1M
Novel adeno-associated virus vector production system developmentR01HL114152 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI XIAO, WEIDONG · 2012 to 2016
$2.2M
Development of highly efficient factor VIII mini-gene therapyR01HL130871 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI XIAO, WEIDONG · 2016 to 2019
$1.9M
Molecular engineering of factor VIII gene for rAAV deliveryR01HL084381 · NHLBI · TEMPLE UNIV OF THE COMMONWEALTH · PI XIAO, WEIDONG · 2008 to 2012
$1.9M
NHLBI NIH HHS R01 HL080789NHLBI NIH HHS R01 HL084381NHLBI NIH HHS R01 HL114152
6 · The paper itself

Abstract

Metagenomics is a trending research area, calling for the need to analyze large quantities of data generated from next generation DNA sequencing technologies. The need to store, retrieve, analyze, share, and visualize such data challenges current online computational systems. Interpretation and annotation of specific information is especially a challenge for metagenomic data sets derived from environmental samples, because current annotation systems only offer broad classification of microbial diversity and function. Moreover, existing resources are not configured to readily address common questions relevant to environmental systems. Here we developed a new online user-friendly metagenomic analysis server called MetaStorm (http://bench.cs.vt.edu/MetaStorm/), which facilitates customization of computational analysis for metagenomic data sets. Users can upload their own reference databases to tailor the metagenomics annotation to focus on various taxonomic and functional gene markers of interest. MetaStorm offers two major analysis pipelines: an assembly-based annotation pipeline and the standard read annotation pipeline used by existing web servers. These pipelines can be selected individually or together. Overall, MetaStorm provides enhanced interactive visualization to allow researchers to explore and manipulate taxonomy and functional annotation at various levels of resolution.

Indexed as

Databases, GeneticMetagenomicsInternet

Identifiers

PMID27632579
PMCPMC5025195

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.