Evidence map›Paper›PMID 27632385›Full record

SynthesisNeuropsychology review2016

Everyday Impact of Cognitive Interventions in Mild Cognitive Impairment: a Systematic Review and Meta-Analysis.

M J Chandler, A C Parks, M Marsiske, L J Rotblatt, G E Smith

Open access · greenAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuropsychology review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed, 8 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 8 syntheses or guidelines pooled it, 173 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Cognitive training for people with mild to moderate dementia.The Cochrane database of systematic reviews · 2019
    Pooled it
  8. Pooled it
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Training gains and transfer effects after mnemonic strategy training in mild cognitive impairment: A fMRI study.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2020
    Trial
  18. Trial
  19. Trial
  20. Trial

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

M J ChandlerMayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA. chandler.melanie@mayo.edu.
A C ParksMayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA.
M MarsiskeUniversity of Florida, Gainesville, FL, USA.
L J RotblattUniversity of Florida, Gainesville, FL, USA.
G E SmithUniversity of Florida, Gainesville, FL, USA.
University of Florida · USMayo Clinic in Florida · US

Funding

Augmenting Cognitive Training in Older Adults - The ACT GrantR01AG054077 · NIA · UNIVERSITY OF FLORIDA · PI COHEN, RONALD A, MARSISKE, MICHAEL · 2016 to 2020
$6.9M
Research Training in Non-Pharmacological Interventions for Cognition in Aging, MCI, and Alzheimer's DiseaseT32AG020499 · NIA · UNIVERSITY OF FLORIDA · PI MARSISKE, MICHAEL, SMITH, GLENN E. · 2003 to 2024
$3.7M
FLUID REASONING TRAINING FOR URBAN ELDERSU01AG014276 · NIA · WAYNE STATE UNIVERSITY · PI MARSISKE, MICHAEL · 1996 to 2010
$2.7M
NIA NIH HHS R01 AG054077NIA NIH HHS T32 AG020499NIA NIH HHS U01 AG014276
6 · The paper itself

Abstract

Cognitive interventions in Mild Cognitive Impairment (MCI) seek to ameliorate cognitive symptoms in the condition. Cognitive interventions may or may not generalize beyond cognitive outcomes to everyday life. This systematic review and meta-analysis sought to assess the effect of cognitive interventions compared to a control group in MCI on generalizability outcome measures [activities of daily living (ADLs), mood, quality of life (QOL), and metacognition] rather than cognitive outcomes alone. PRISMA guidelines were followed. MEDLINE and PsychInfo were utilized as data sources to locate references related to cognitive interventions in individuals with MCI. The cognitive intervention study was required to have a control or alternative treatment comparison group to be included. Thirty articles met criteria, including six computerized cognitive interventions, 14 therapist-based interventions, and 10 multimodal (i.e., cognitive intervention plus an additional intervention) studies. Small, but significant overall median effects were seen for ADLs (d = 0.23), mood (d = 0.16), and metacognitive outcomes (d = 0.30), but not for QOL (d = 0.10). Computerized studies appeared to benefit mood (depression, anxiety, and apathy) compared to controls, while therapist-based interventions and multimodal interventions had more impact on ADLs and metacognitive outcomes than control conditions. The results are encouraging that cognitive interventions in MCI may impact everyday life, but considerably more research is needed. The current review and meta-analysis is limited by our use of only PsychInfo and MEDLINE databases, our inability to read full text non-English articles, and our reliance on only published data to complete effect sizes.

Indexed as

Cognitive Behavioral TherapyActivities of Daily LivingCognitive DysfunctionHumansQuality of LifeActivities of daily livingCognitive interventionMild Cognitive ImpairmentQuality of life; systematic review; meta-analysis

Identifiers

PMID27632385
PMCPMC5048589
OpenAlexW2511779346

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.