Evidence map›Paper›PMID 27632382›Full record

Trial reportEuropean journal of applied physiology2016

Effects of training and detraining on adiponectin plasma concentration and muscle sensitivity in lean and overweight men.

Caroline Gastebois, Clément Villars, Jocelyne Drai, Emmanuelle Canet-Soulas, Stéphane Blanc, Audrey Bergouignan, Etienne Lefai, Chantal Simon

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Effects of a four week detraining period on physical, metabolic, and inflammatory profiles of elderly women who regularly participate in a program of strength training.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2020
    Article
  5. Adiponectin-Consideration for its Role in Skeletal Muscle Health.International journal of molecular sciences · 2019
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Caroline GasteboisCARMEN, INSERM U1060, University of Lyon 1, INRA1235, CRNH-RA, 69600, Oullins, France.
Clément VillarsCARMEN, INSERM U1060, University of Lyon 1, INRA1235, CRNH-RA, 69600, Oullins, France.
Jocelyne DraiCARMEN, INSERM U1060, University of Lyon 1, INRA1235, CRNH-RA, 69600, Oullins, France.
Emmanuelle Canet-SoulasCARMEN, INSERM U1060, University of Lyon 1, INRA1235, CRNH-RA, 69600, Oullins, France.
Stéphane BlancIPHC CNRS, UMR 7178, University of Strasbourg, 67087, Strasbourg, France.
Audrey BergouignanIPHC CNRS, UMR 7178, University of Strasbourg, 67087, Strasbourg, France.
Etienne LefaiCARMEN, INSERM U1060, University of Lyon 1, INRA1235, CRNH-RA, 69600, Oullins, France.
Chantal SimonCARMEN, INSERM U1060, University of Lyon 1, INRA1235, CRNH-RA, 69600, Oullins, France. chantal.simon@univ-lyon1.fr.
Inserm · FRUniversité Claude Bernard Lyon 1 · FRLaboratoire CarMeN · FRTexas Diabetes & Endocrinology · USUniversité de Strasbourg · FR

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Edward L Melanson · 1995 to 2026
$32.6M
NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

purposeTo delineate the direct effect of physical activity on adiponectin metabolism, we investigated the impact of contrasted physical activity changes, independent of body mass changes, on adiponectin plasma concentration and muscle sensitivity in lean and overweight adult males.

methodsEleven physically active lean men (70.6 ± 2.1 kg) were subjected to 1-month detraining; 9 sedentary lean men (73.1 ± 3.3 kg); and 11 sedentary overweight men (97.5 ± 3.0 kg) participated in a 2-month aerobic-exercise training program. Diet was controlled to maintain stable energy balance. Body composition, VO

resultsAt baseline, plasma high-molecular-weight adiponectin concentration was lower in both active lean (5.44 ± 0.58 µg/mL) and sedentary overweight (5.30 ± 1.06 µg/mL) than in sedentary lean participants (7.44 ± 1.06 µg/mL; both p < 0.05). Training reduced total and high-molecular-weight adiponectin concentrations by, respectively, -32 and -42 % in sedentary lean, and -26 and -35 % in sedentary overweight, while detraining increased them by +25 and +27 % in active lean participants. Total and high-molecular-weight adiponectin changes were inversely correlated with VO

conclusionPlasma adiponectin concentration is inversely correlated with aerobic capacity. Future investigations will need to confirm the contribution of changes in muscle adiponectin sensitivity.

Indexed as

Sedentary BehaviorAdaptation, PhysiologicalAdiponectinExercise TherapyHumansMaleMuscle, SkeletalOverweightPhysical Conditioning, HumanThinnessAdiponectinADIPOQ protein, humanAdiponectin receptorsAerobic fitnessBody weightExerciseMultimeric forms

Identifiers

PMID27632382
OpenAlexW2507123781

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.