Evidence map›Paper›PMID 27632371›Full record

ArticleBritish journal of cancer2016

Dairy, calcium, vitamin D and ovarian cancer risk in African-American women.

Bo Qin, Patricia G Moorman, Anthony J Alberg, Jill S Barnholtz-Sloan, Melissa Bondy, Michele L Cote, Ellen Funkhouser, Edward S Peters, Ann G Schwartz, Paul Terry and 2 more

Open access · hybridAbstract read
In one paragraph

Article in British journal of cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. Review
  7. Lifestyle-Based Approaches to Cancer Prevention and Treatment: Diet, Physical Activity, and Integrative Strategies.Pathophysiology : the official journal of the International Society for Pathophysiology · 2025
    Review
  8. Review
  9. Cancer Prevention and Treatment Based on Lifestyles.Cancer treatment and research · 2024
    Review
  10. Prevention of Epithelial Ovarian Cancer.Cold Spring Harbor perspectives in medicine · 2023
    Review
  11. Integrative Medicine for Ovarian Cancer.Current oncology reports · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Vitamin D Exposure and Ovarian Cancer Risk and Prognosis.International journal of environmental research and public health · 2020
    Review
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 12 institutions in 1 country.

Bo QinPopulation Science, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
Patricia G MoormanDepartment of Community and Family Medicine, Duke Cancer Institute, Durham, NC 27705, USA.
Anthony J AlbergHollings Cancer Center and Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC 29425, USA.
Jill S Barnholtz-SloanCase Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.
Melissa BondyCancer Prevention and Population Sciences Program, Baylor College of Medicine, Houston, TX 77030, USA.
Michele L CoteDepartment of Oncology and the Karmanos Cancer Institute, Population Studies and Disparities Research Program, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Ellen FunkhouserDivision of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA.
Edward S PetersEpidemiology Program, Louisiana State University Health Sciences Center School of Public Health, New Orleans, LA 70112, USA.
Ann G SchwartzDepartment of Oncology and the Karmanos Cancer Institute, Population Studies and Disparities Research Program, Wayne State University School of Medicine, Detroit, MI 48201, USA.
Paul TerryDepartments of Public Health and Surgery, University of Tennessee-Knoxville, Knoxville, TN 37996, USA.
Joellen M SchildkrautDepartment of Public Health Sciences, University of Virginia, Charlottesville, VA 22908, USA.
Elisa V BanderaPopulation Science, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA.
Baylor College of Medicine · USCase Western Reserve University · USDuke Cancer InstituteKnoxville College · USLouisiana State University Health Sciences Center New Orleans · USMedical University of South Carolina · USRutgers Cancer Institute of New JerseyRutgers, The State University of New Jersey · USThe Barbara Ann Karmanos Cancer Institute · USUniversity of Alabama at Birmingham · USUniversity of Virginia · USWayne State University · US

Funding

TRANSCRIPTIONAL PROFILINGP30CA072720 · NCI · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI Chang S Chan · 1997 to 2026
$94.5M
Tumor Biology and Microenvironment (Program 1)P30CA022453 · NCI · WAYNE STATE UNIVERSITY · PI PAUL M STEMMER · 1985 to 2026
$68.4M
NEW JERSEY CANCER PREVENTION & CONTROL PROGRAMU58DP003931 · DP · NEW JERSEY STATE DEPT/HEALTH/SENIOR SRVS · PI RODRIQUEZ, GLORIA · 2012 to 2014
$11.9M
Epidemiology of Ovarian Cancer in African-American WomenR01CA142081 · NCI · UNIVERSITY OF VIRGINIA · PI SCHILDKRAUT, JOELLEN M. · 2010 to 2015
$10.6M
NCCDPHP CDC HHS U58 DP003931NCI NIH HHS HHSN261201000028CNCI NIH HHS HHSN261201300021CNCI NIH HHS P30 CA022453NCI NIH HHS P30 CA072720NCI NIH HHS R01 CA142081
6 · The paper itself

Abstract

backgroundNo previous study has evaluated the associations of dairy products, lactose, calcium and vitamin D with the risk of ovarian cancer in African-American women, who are known to have high mortality from the disease, as well as to be at risk for calcium and vitamin D deficiency.

methodsWe evaluated these associations among 490 ovarian cancer cases and 656 age- and site-matched controls of African-American descent recruited into the African American Cancer Epidemiology Study, a population-based case-control study in 11 geographical areas in the US. Multivariable logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs).

resultsAn increased ovarian cancer risk was observed for whole milk consumption and lactose intake (highest quartile vs lowest: OR=1.97, 95% CI: 1.25-3.10;P-trend: 0.008). Calcium intake was associated with a decreased risk of ovarian cancer (OR=0.51, 95 CI%: 0.30-0.86; P-trend: 0.009), but vitamin D intake was not. Longer sun exposure in summer months was found to predict a lower risk (OR=0.71, 95% CI: 0.51-0.99; P-trend: 0.049).

conclusionsOur findings suggest that a high-calcium, low-lactose diet, and sun exposure in summer months may reduce the risk of ovarian cancer in African-American women.

Indexed as

AdultAgedBlack or African AmericanCalcium, DietaryCase-Control StudiesDairy ProductsFemaleHumansMiddle AgedNutrition SurveysOvarian NeoplasmsRisk FactorsUnited StatesVitamin DVitamin D DeficiencyYoung AdultCalcium, DietaryVitamin D

Identifiers

PMID27632371
PMCPMC5117784
OpenAlexW2520417877

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.