Evidence map›Paper›PMID 27632078›Full record

ArticleJournal of neurologic physical therapy : JNPT2016

Alterations in Aerobic Exercise Performance and Gait Economy Following High-Intensity Dynamic Stepping Training in Persons With Subacute Stroke.

Abigail L Leddy, Mark Connolly, Carey L Holleran, Patrick W Hennessy, Jane Woodward, Ross A Arena, Elliot J Roth, T George Hornby

2 registry-linked trialsAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neurologic physical therapy : JNPT, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 24 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05720013 nacompletednot on this mapstarted 2023, after this paper: background citation

Acute Effects of Beetroot Juice on Locomotor Economy and Capacity in Chronic Stroke

TypeinterventionalSponsorIndiana UniversityRan2023 to 2023Enrolled22ConditionsStroke, CVAArmsBeetroot Juice supplement, Placebo supplement
NCT05727930 narecruitingnot on this mapstarted 2023, after this paper: background citation

Variable Intensive Early Walking Post-Stroke -2 (VIEWS-2)

TypeinterventionalSponsorIndiana UniversityRan2023 to 2028Enrolled100ConditionsStrokeArmsHigh-intensity, task-specific (i.e., walking) interventions, High-intensity, non-specific physical therapy interventions, Low-intensity, task-specific physical therapy interventions, Low-intensity, non-specific physical therapy interventions
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  3. Physical fitness training for stroke patients.The Cochrane database of systematic reviews · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Abigail L LeddySensory Motor Performance Program (A.L.L., M.C., C.L.H., P.W.H., J.W., T.G.H.), Rehabilitation Institute of Chicago, Chicago, Illinois; Department of Physical Medicine and Rehabilitation (R.A.A., E.J.R., T.G.H.), Feinberg School of Medicine, Northwestern University, Chicago, Illinois; Department of Physical Therapy and Kinesiology & Nutrition (R.A.A.), University of Illinois at Chicago; and Department of Physical Medicine and Rehabilitation (T.G.H.), Indiana University School of Medicine, Indianapolis, Indiana.
Mark Connolly
Carey L Holleran
Patrick W Hennessy
Jane Woodward
Ross A Arena
Elliot J Roth
T George Hornby

Funding

Reflex Regulation of Motor function in Human SCIR01NS062982 · NINDS · MARQUETTE UNIVERSITY · PI HORNBY, THOMAS GEORGE, SCHMIT, BRIAN D · 2009 to 2010
$773k
NINDS NIH HHS R01 NS062982
6 · The paper itself

Abstract

background and purposeImpairments in metabolic capacity and economy (O2cost) are hallmark characteristics of locomotor dysfunction following stroke. High-intensity (aerobic) training has been shown to improve peak oxygen consumption in this population, with fewer reports of changes in O2cost. However, particularly in persons with subacute stroke, inconsistent gains in walking function are observed with minimal associations with gains in metabolic parameters. The purpose of this study was to evaluate changes in aerobic exercise performance in participants with subacute stroke following high-intensity variable stepping training as compared with conventional therapy.

methodsA secondary analysis was performed on data from a randomized controlled trial comparing high-intensity training with conventional interventions, and from the pilot study that formed the basis for the randomized controlled trial. Participants 1 to 6 months poststroke received 40 or fewer sessions of high-intensity variable stepping training (n = 21) or conventional interventions (n = 12). Assessments were performed at baseline (BSL), posttraining, and 2- to 3-month follow-up and included changes in submaximal (Equation is included in full-text article.)O2 ((Equation is included in full-text article.)O2submax) and O2cost at fastest possible treadmill speeds and peak speeds at BSL testing.

resultsSignificant improvements were observed in (Equation is included in full-text article.)O2submax with less consistent improvements in O2cost, although individual responses varied substantially. Combined changes in both (Equation is included in full-text article.)O2submax and (Equation is included in full-text article.)O2 at matched peak BSL speeds revealed stronger correlations to improvements in walking function as compared with either measure alone. DISCUSSION AND

conclusionsHigh-intensity stepping training may elicit significant improvements in (Equation is included in full-text article.)O2submax, whereas changes in both peak capacity and economy better reflect gains in walking function. Providing high-intensity training to improve locomotor and aerobic exercise performance may increase the efficiency of rehabilitation sessions.Video Abstract available for more insights from the authors (see Supplemental Digital Content, http://links.lww.com/JNPT/A142).

Indexed as

ExerciseStroke RehabilitationExercise TestExercise TherapyHumansMotor Skills DisordersParesisRandomized Controlled Trials as TopicStroke

Identifiers

PMID27632078
PMCPMC5026397

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.