Evidence map›Paper›PMID 27632002›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2016

Reconstitution of COPI Vesicle and Tubule Formation.

Seung-Yeol Park, Jia-Shu Yang, Victor W Hsu

Open access · greenAbstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Seung-Yeol ParkDivision of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Jia-Shu YangDivision of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, 02115, USA.
Victor W HsuDivision of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Boston, MA, 02115, USA. vhsu@bwh.harvard.edu.
Brigham and Women's Hospital · US

Funding

Mechanisms and Physiology of COPI TransportR37GM058615 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI HSU, VICTOR W · 2016 to 2025
$6.0M
COPI TransportR01GM058615 · NIGMS · BRIGHAM AND WOMEN'S HOSPITAL · PI HSU, VICTOR W · 2001 to 2015
$5.7M
NIGMS NIH HHS R01 GM058615NIGMS NIH HHS R37 GM058615
6 · The paper itself

Abstract

The Golgi complex plays a central role in the intracellular sorting of proteins. Transport through the Golgi in the anterograde direction has been explained by cisternal maturation, while transport in the retrograde direction is attributed to vesicles formed by the coat protein I (COPI) complex. A more detailed understanding of how COPI acts in Golgi transport is being achieved in recent years, due in large part to a COPI reconstitution system. Through this approach, the mechanistic complexities of COPI vesicle formation are being elucidated. This approach has also uncovered a new mode of anterograde transport through the Golgi, which involves COPI tubules connecting the Golgi cisternae. We describe in this chapter the reconstitution of COPI vesicle and tubule formation from Golgi membrane.

Indexed as

Coat Protein Complex ICOP-Coated VesiclesGolgi ApparatusAnimalsBiological Transport, ActiveHumansCoat Protein Complex IARFCOPIGolgi complexTubule formationVesicle formation

Identifiers

PMID27632002
PMCPMC6779305
OpenAlexW2513474373

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.