Evidence map›Paper›PMID 27631876›Full record

ArticleMolecular neurobiology2017

High-Resolution Expression Profiling of Peripheral Blood CD8

Luisa Roch, Michael Hecker, Jörg Friess, Ines Charlotte Angerer, Dirk Koczan, Brit Fitzner, Ina Schröder, Kristin Flechtner, Hans-Jürgen Thiesen, Stefanie Meister and 2 more

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Luisa RochDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
Michael HeckerDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany. michael.hecker@rocketmail.com.
Jörg FriessDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
Ines Charlotte AngererDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
Dirk KoczanInstitute of Immunology, University of Rostock, Schillingallee 70, 18057, Rostock, Germany.
Brit FitznerSteinbeis Transfer Center for Proteome Analysis, Schillingallee 70, 18057, Rostock, Germany.
Ina SchröderDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
Kristin FlechtnerInstitute of Immunology, University of Rostock, Schillingallee 70, 18057, Rostock, Germany.
Hans-Jürgen ThiesenSteinbeis Transfer Center for Proteome Analysis, Schillingallee 70, 18057, Rostock, Germany.
Stefanie MeisterDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
Alexander WinkelmannDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
Uwe Klaus ZettlDepartment of Neurology, Division of Neuroimmunology, University of Rostock, Gehlsheimer Str. 20, 18147, Rostock, Germany.
University of Rostock · DESteinbeis Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fingolimod, a sphingosine-1-phosphate (S1P) receptor modulator, is an oral drug approved for the treatment of active relapsing-remitting multiple sclerosis (RRMS). It selectively inhibits the egress of lymphocytes from lymph nodes. We studied the changes in the transcriptome of peripheral blood CD8

Indexed as

AdultCD8-Positive T-LymphocytesCytokinesCytotoxicity, ImmunologicFemaleFingolimod HydrochlorideHumansLysophospholipidsMaleMiddle AgedMultiple SclerosisPhenotypeSphingosineCytokinesFingolimod HydrochlorideLysophospholipidsSphingosinesphingosine 1-phosphateCD8+ T cellsFingolimodPeripheral bloodRelapsing-remitting multiple sclerosisSphingosine-1-phosphateTranscriptome profiling

Identifiers

PMID27631876
OpenAlexW2517722360

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.