ArticlePloS one2016
Oxygenation Threshold Derived from Near-Infrared Spectroscopy: Reliability and Its Relationship with the First Ventilatory Threshold.
Article in PloS one, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.
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Who cites it
44 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Reliability of threshold determination using portable muscle oxygenation monitors during exercise testing: a systematic review and meta-analysis.Scientific reports · 2023Pooled it
- A heat and moisture-exchanging mask impairs self-paced maximal running performance in a sub-zero environment.European journal of applied physiology · 2021Trial
- Effects of Vibration and Non-Vibration Foam Rolling on Recovery after Exercise with Induced Muscle Damage.Journal of sports science & medicine · 2019Trial
- Visually identified breakpoints in muscle oxygen saturation are not equivalent to ventilatory thresholds in national-level triathletes.European journal of applied physiology · 2026Article
- Observational
- Distinguishing Muscle Oxygen Saturation from Tissue Oxygen Saturation: Accuracy, Limitations, and Practical Utility in Muscle Oximetry.Sports medicine - open · 2026Article
- Skeletal Muscle Blood Flow and NIRS Oxygenation Kinetics as a Tool to Evaluate Adaptations to High-Intensity Exercise Training.Sensors (Basel, Switzerland) · 2026Article
- Agreement between muscle saturation breakpoints and lactate thresholds: Muscles comparison and sex difference in world-class Nordic skiers.Experimental physiology · 2026Article
- Validation of muscle oxygenation kinetics to predict aerobic fitness and exercise transition thresholds.Experimental physiology · 2026Article
- Exploration of the associations between muscle oxygen saturation and skin temperature responses during isokinetic strength exercise.PloS one · 2026Article
- Test-Retest Reliability and Sex-Dependent Responses for Physiological and Perceptual Variables at Sub-Maximal Thresholds.Journal of functional morphology and kinesiology · 2025Article
- Continuous Monitoring of Muscle Oxygenation in Endurance Athletes During Incremental Cycling: Experimental Validation of a Wearable Continuous-Wave NIRS Sensor Using Frequency-Domain Near-Infrared Spectroscopy.Bioengineering (Basel, Switzerland) · 2025Article
- Assessing the feasibility of near-infrared spectroscopy for evaluating physiological exercise thresholds.Scientific reports · 2025Article
- Validity and Practical Application of Muscle Oxygenation Monitoring for Identifying Maximal Fat Oxidation in Cyclists.European journal of sport science · 2025Article
- Effects of an 8-week high intensity interval training (HIIT) and ashwagandha supplementation on aerobic capacity, muscle oxygenation and haematological parameters in healthy men.Biology of sport · 2025Article
- The impact of skinfold thickness and exercise intensity on the reliability of NIRS in the vastus lateralis.European journal of applied physiology · 2025Article
- Evaluation of leg symmetry in muscle oxygen saturation during submaximal to maximal cycling exercise.European journal of sport science · 2025Article
- Profiles of muscle-specific oxygenation responses and thresholds during graded cycling incremental test.European journal of applied physiology · 2025Article
- The relationship and agreement between systemic and local breakpoints in locomotor and non-locomotor muscles during single-leg cycling.Frontiers in physiology · 2025Article
- Agreement between Ventilatory Thresholds and Bilaterally Measured Vastus Lateralis Muscle Oxygen Saturation Breakpoints in Trained Cyclists: Effects of Age and Performance.Sports (Basel, Switzerland) · 2024Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNear-infrared spectroscopy (NIRS) measurements of oxygenation reflect O2 delivery and utilization in exercising muscle and may improve detection of a critical exercise threshold. PURPOSE: First, to detect an oxygenation breakpoint (Δ[O2HbMb-HHbMb]-BP) and compare this breakpoint to ventilatory thresholds during a maximal incremental test across sexes and training status. Second, to assess reproducibility of NIRS signals and exercise thresholds and investigate confounding effects of adipose tissue thickness on NIRS measurements.
methodsForty subjects (10 trained male cyclists, 10 trained female cyclists, 11 endurance trained males and 9 recreationally trained males) performed maximal incremental cycling exercise to determine Δ[O2HbMb-HHbMb]-BP and ventilatory thresholds (VT1 and VT2). Muscle haemoglobin and myoglobin O2 oxygenation ([HHbMb], [O2HbMb], SmO2) was determined in m. vastus lateralis. Δ[O2HbMb-HHbMb]-BP was determined by double linear regression. Trained cyclists performed the maximal incremental test twice to assess reproducibility. Adipose tissue thickness (ATT) was determined by skinfold measurements.
resultsΔ[O2HbMb-HHbMb]-BP was not different from VT1, but only moderately related (r = 0.58-0.63, p<0.001). VT1 was different across sexes and training status, whereas Δ[O2HbMb-HHbMb]-BP differed only across sexes. Reproducibility was high for SmO2 (ICC = 0.69-0.97), Δ[O2HbMb-HHbMb]-BP (ICC = 0.80-0.88) and ventilatory thresholds (ICC = 0.96-0.99). SmO2 at peak exercise and at occlusion were strongly related to adipose tissue thickness (r2 = 0.81, p<0.001; r2 = 0.79, p<0.001). Moreover, ATT was related to asymmetric changes in Δ[HHbMb] and Δ[O2HbMb] during incremental exercise (r = -0.64, p<0.001) and during occlusion (r = -0.50, p<0.05).
conclusionAlthough the oxygenation threshold is reproducible and potentially a suitable exercise threshold, VT1 discriminates better across sexes and training status during maximal stepwise incremental exercise. Continuous-wave NIRS measurements are reproducible, but strongly affected by adipose tissue thickness.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.