ReviewJournal of gastrointestinal cancer2016
Primary Leiomyosarcoma of the Pancreas-a Case Report and a Comprehensive Review.
Review in Journal of gastrointestinal cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 15 citations in OpenAlex.
- Pancreatic Tail Leiomyosarcoma With Hepatic Metastases: Diagnostic and Therapeutic Challenges: A Case Report.Clinical medicine insights. Case reports · 2026Article
- Rare Solid Pancreatic Lesions on Cross-Sectional Imaging.Diagnostics (Basel, Switzerland) · 2023Review
- Leiomyosarcoma, a rare smooth muscle cancer in the pancreas: An adjuvant radiotherapy treatment approach.Cancer reports (Hoboken, N.J.) · 2023Article
- Natural History and Treatment Trends in Pancreatic Cancer Subtypes.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019Article
- Irreversible electroporation in a case of pancreatic leiomyosarcoma: a novel weapon versus a rare malignancy?World journal of surgical oncology · 2019Article
- Leiomyosarcoma Involving the Pancreas Diagnosed by Endoscopic Ultrasound Fine-Needle Aspiration.Journal of gastrointestinal cancer · 2018Article
- A case report of primary pancreatic leiomyosarcoma requiring six additional resections for recurrences.International journal of surgery case reports · 2017Article
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePrimary mesenchymal tumors of the pancreas are rare, with leiomyosarcomas the most encountered entities among the pancreatic sarcomas. With few exceptions, single case reports published over the last six decades constitute the entire scientific literature on this topic. Thus, evidence regarding clinical decision-making is scant.
methodsBased on a case report and an extensive literature search in PubMed, we discuss the clinical aspects and current management of this rare malignancy.
resultsWe identified only two papers with more than a single case presentation; these institutional patient series were limited to five and nine patients. Additionally, a few papers sought to summarize the individual case reports published in the English and/or Chinese language. The clinical presentation is rather non-specific. Moreover, modern imaging modalities are insufficiently accurate to diagnose leiomyosarcoma of the pancreas. Treatment goals include a complete resection with free margins. Proper morphologic examination using immunohistochemistry and the application of a grading system are clinically important for prognostication. The efficacy of adjuvant treatments has not been established.
conclusionPrimary pancreatic leiomyosarcoma is extremely rare, and the scientific literature is primarily based on single case reports. Conclusions on management and prognosis should be drawn with caution. A multidisciplinary team consultation is warranted to discuss a thorough individual treatment plan based on the available scientific literature, despite its low evidence level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.