ArticleJournal of racial and ethnic health disparities2016
Racial Differences Among Factors Associated with Participation in Clinical Research Trials.
Article in Journal of racial and ethnic health disparities, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Trial
- Article
- Understanding Motivation to Participate in Clinical Trials: Insights to Diversify Clinical Research Using Health Information National Trends Survey.Clinical and translational science · 2026Article
- Improving Recruitment Into Research Studies via Electronically Collected Patient-Entered Data: Mixed Methods Study.Journal of medical Internet research · 2025Article
- Mixed-Methods Approach: Impact of Clinical Consenter Diversity on Clinical Trials Enrollment.Cancers · 2025Article
- Patient participation in clinical trials conducted by principal investigators who speak one or more language(s) beyond english: Exploring ethnicity as proxy for language.Contemporary clinical trials communications · 2024Article
- Cryptocurrency as a new method for participant compensation in research.Health policy and technology · 2023Article
- Formative research to promote lupus awareness and early screening at Historically Black College and University (HBCU) communities in South Carolina.BMC rheumatology · 2022Article
- Recommendations to encourage participation of individuals from diverse backgrounds in psychiatric genetic studies.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2022Review
- Results from a Theory-Guided Survey to Support Breast Cancer Trial Participation: Barriers, Enablers, and What to Do about them.Current oncology (Toronto, Ont.) · 2021Article
- Sex Differences in Willingness to Participate in Research Based on Study Risk Level Among a Community Sample of African Americans in North Central Florida.Journal of immigrant and minority health · 2021Article
- Article
- Impact of Race Versus Education and Race Versus Income on Patients' Motivation to Participate in Clinical Trials.Journal of racial and ethnic health disparities · 2018Article
- Cancer Health Literacy and Willingness to Participate in Cancer Research and Donate Bio-Specimens.International journal of environmental research and public health · 2018Article
- Underrepresentation of Hispanics and Other Minorities in Clinical Trials: Recruiters' Perspectives.Journal of racial and ethnic health disparities · 2018Article
- Research Professionals' Perspectives, Barriers, and Recommendations Regarding Minority Participation in Clinical Trials.Journal of racial and ethnic health disparities · 2017Article
- Barriers and Strategies for Recruitment of Racial and Ethnic Minorities: Perspectives from Neurological Clinical Research Coordinators.Journal of racial and ethnic health disparities · 2017Article
- Factors Influencing Participation in Clinical Trials: Emergency Medicine vs. Other Specialties.The western journal of emergency medicine · 2017Article
- US Military Service Members' Reasons for Deciding to Participate in Health Research.Research in nursing & health · 2017Article
- Perceptions and Preferences Regarding Multiple Sclerosis Research Among Racial and Ethnic Groups.International journal of MS careArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo identify whether racial differences exist among various factors associated with patients' decision to participate in clinical research trials.
methodsA self-administered, IRB-approved survey was utilized with inclusion criteria requiring subjects to be 18 years of age or older, having active patient status and ability to complete the survey without assistance. Subjects were asked to rate potential influential motivators, barriers, and facilitators on a "no influence" (0) to "most influence" (4) scale for participation in research that tests a new drug or device. Kruskal-Wallis testing was used to identify factors significantly associated with race.
resultsAnalysis included 1643 surveys: 949 (57.8 %) Caucasian; 217 (13.2 %) African-American; 317 (19.3 %) Hispanic; 62 (3.8 %) Multiracial; and 98 (6.0 %) "Other" minorities. Statistically significant differences (p ≤ .02) by race were found for five out of ten motivating factors. "How well the research study is explained to me" had the highest mean value for all races except other minorities, for whom "Knowledge learned from my participation will benefit someone in the future" scored highest. "Risk of unknown side-effects" was the greatest barrier for all races.
conclusionRacial differences exist not only between Caucasians and Minorities for the factors associated with their clinical trial participation, but also among different minority races themselves. To promote diversity in research, recruitment strategies for each individual race should be customized based on what matters to the target population.
Indexed as
Identifiers
27631379What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.