Evidence map›Paper›PMID 27631317›Full record

ArticleSurgical endoscopy2017

Laparoscopic wedge resection for suspected large (≥5 cm) gastric gastrointestinal stromal tumors.

Chun Yuet Khoo, Brian K P Goh, Alvin K H Eng, Weng-Hoong Chan, Melissa C C Teo, Alexander Y F Chung, Hock-Soo Ong, Wai-Keong Wong

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05938309 (A Prospective, Multicenter Cohort Study on the Efficacy and Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal Tumors), which is not on this map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05938309 recruitingnot on this mapstarted 2023, after this paper: background citation

A Prospective, Multicenter Cohort Study on the Efficacy and Safety of Laparoscopic Resection of 5cm or Larger Gastric Gastrointestinal Stromal Tumors

TypeobservationalSponsorFujian Medical UniversityRan2023 to 2028Enrolled194ConditionsGastrointestinal Stromal Tumors
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. LAPAROSCOPIC VERSUS OPEN SURGERY IN GASTRIC GASTROINTESTINAL STROMAL TUMORS LARGER THAN 5 CM: A SYSTEMATIC REVIEW AND META-ANALYSIS.Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2023
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  14. Laparoscopic treatment of large gastrointestinal stromal tumors (> 5 cm).Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Chun Yuet KhooDepartment of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia Level 5, Singapore, 169856, Singapore.
Brian K P GohDepartment of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia Level 5, Singapore, 169856, Singapore. bsgkp@hotmail.com.
Alvin K H EngDepartment of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, Singapore, Singapore.
Weng-Hoong ChanDepartment of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, Singapore, Singapore.
Melissa C C TeoDivision of Surgical Oncology, National Cancer Center Singapore, Singapore, Singapore.
Alexander Y F ChungDepartment of Hepatopancreatobiliary and Transplantation Surgery, Singapore General Hospital, 20 College Road, Academia Level 5, Singapore, 169856, Singapore.
Hock-Soo OngDepartment of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, Singapore, Singapore.
Wai-Keong WongDepartment of Upper Gastrointestinal and Bariatric Surgery, Singapore General Hospital, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaparoscopic wedge resection (LWR) for small gastric gastrointestinal stromal tumors (GIST) is now widely accepted, but its application for large GISTs remains controversial. This study aims to evaluate the feasibility and safety of LWR for suspected large (≥5 cm) gastric GISTs.

methodsRetrospective review of 82 consecutive patients who underwent attempted LWR for suspected gastric GIST. LWR for large (≥5 cm) (n = 23) tumors was compared with LWR for small (<5 cm) tumors (n = 59). The 23 patients with LWR for large tumors were also compared to 36 consecutive patients who underwent open wedge resection (OWR) for large tumors.

resultsComparison between patients who underwent LWR for large versus small tumors demonstrated that resection of large tumors was associated with a longer operating time. There was no difference in other perioperative outcomes, and oncological outcomes such as frequency of close margins (≤1 mm) and recurrence-free survival. Comparison between patients who underwent LWR versus OWR for large tumors showed that LWR was associated with decreased median time to fluid or solid diet, shorter postoperative stay but longer operating times. There was no difference in oncological outcomes.

conclusionLWR for suspected large gastric GIST is feasible and safe. It is associated with similar short-term outcomes with LWR for small tumors and favorable short-term outcomes over OWR for large tumors without compromising on oncological outcomes.

Indexed as

AdultAgedAged, 80 and overFeasibility StudiesFemaleGastrectomyGastrointestinal Stromal TumorsHumansLaparoscopyMaleMiddle AgedOperative TimePostoperative PeriodRetrospective StudiesStomach NeoplasmsGastrointestinal stromal tumorsLaparoscopic resectionLaparoscopyLargeWedge resection

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.