Observational studyMedicine2016
Different surgical strategies of patients with intravenous leiomyomatosis.
Observational study in Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.
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Who cites it
55 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.
- The role of estrogen deprivation therapy in premenopausal women with primary unresectable intracardiac leiomyomatosis: a systematic review and meta-analysis.Orphanet journal of rare diseases · 2021Pooled it
- Intravenous leiomyomatosis: A retrospective case series of imaging findings and diagnostic challenges.Radiology case reports · 2026Article
- Transesophageal Echocardiography-Guided Anesthetic Management of Intravenous Leiomyomatosis With Right Atrial Extension: A Case Report.A&A practice · 2026Article
- Case report of the management of intravascular leiomyomatosis including uterine surgery, vascular surgery, hormonal management, and in vitro fertilization.Journal of vascular surgery cases and innovative techniques · 2026Article
- Ultrasonic typing and diagnostic value of intravenous leiomyomatosis: a single-center retrospective study.Frontiers in oncology · 2026Article
- Multidisciplinary management of intravenous leiomyomatosis extending to the inferior vena cava and heart: a case series.BMC cardiovascular disorders · 2025Article
- Leiomyomas beyond the uterus presenting with multiple growth patterns in a single patient.BMC women's health · 2025Article
- Multistage Excision of Intravascular Leiomyoma With Extension Into the Right Atrium.JACC. Case reports · 2025Article
- Ultrasound diagnostic value and clinical analysis of 61 uterine intravenous leiomyomatosis cases.Quantitative imaging in medicine and surgery · 2025Article
- Puzzling obstructive tumor in the right heart: A large intravascular leiomyomatosis with intracardiac extension.Global cardiology science & practice · 2025Article
- A complex clinical case of intracardiac leiomyomatosis.BMC cardiovascular disorders · 2025Article
- Intravenous leiomyomatosis presenting as Budd-Chiari syndrome: a case report and literature review.Orphanet journal of rare diseases · 2025Review
- Intravascular leiomyomatosis in postmenopausal woman: a case report.Frontiers in medicine · 2025Article
- Intravenous leiomyomatosis involving the inferior vena cava and right atrium with postoperative pulmonary embolism: a case report.Frontiers in surgery · 2025Article
- The largest single-center report on intravenous leiomyomatosis and development of a classification to guide surgical management.Journal of vascular surgery. Venous and lymphatic disorders · 2025Article
- Intravenous Leiomyomatosis of the Uterus: An Intriguing Case Revealed through Anatomopathological Examination.La Tunisie medicale · 2024Article
- Surgical strategy for intravenous leiomyomatosis spreading from uterine to the right atrium presenting with recurrent syncope.Journal of cardiothoracic surgery · 2024Article
- A case report: intravenous leiomyomatosis extending from the uterus to the right atrium.Annals of medicine and surgery (2012) · 2024Article
- MR imaging findings of stage I intravenous leiomyomatosis: a retrospective single-center study in 19 cases.Abdominal radiology (New York) · 2024Article
- Unraveling the challenges of intravenous leiomyomatosis: a retrospective analysis of 11 cases.Archives of gynecology and obstetrics · 2024Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intravenous leiomyomatosis (IVL) is a rare benign tumor. The study aimed to assess outcomes of patients treated surgically for IVL.Between November 2002 and January 2015, 76 patients were treated for IVL. The stage of IVL was evaluated preoperatively by echocardiography and enhanced computerized tomography (CT) scan, and graded into 4 stages according to intravascular tumor progression. We recorded age, lower limb edema before surgery, surgical parameters, and hospitalization expenses. Patients were followed up every 6 months and tumor recurrence was assessed by CT and ultrasound. Patients were followed up for a mean of 4.5 ± 2.5 years (range 1-13 years) and there was no operative, hospital, or long-term mortality or were lost to follow-up.The rate of lower extremity edema, amount of blood loss, postoperative transfusion, length of intensive care unit (ICU) stay, postoperative hospitalization, and hospitalization expenses differed significantly between patients at different presurgery stages. Tumors recurred in 4 of 7 patients with stage I IVL that opted for surgery that preserved the ovaries and uterus. No recurrence was observed in patients graded stage II or more, in all of which the uterus and ovaries were removed. Recurrence was observed in only 4 of 76 cases of IVL, all of whom opted for surgery that spared the ovaries and uterus.Different surgical strategies should be decided based on the staging to completely remove the tumor and ensure the safety of patients. Removal of both ovaries is necessary for inhibiting tumor growth and avoiding recurrence.
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