ArticleJACC. Basic to translational science2016
Real-time magnetic resonance imaging guidance improves the diagnostic yield of endomyocardial biopsy.
Article in JACC. Basic to translational science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Interventional cardiac magnetic resonance imaging: current applications, technology readiness level, and future perspectives.Therapeutic advances in cardiovascular diseasePooled it
- Advancements in Cardiac Catheterization Safety: Novel Radiation Protection Approaches Redefining Occupational Health.Current cardiology reviews · 2025Review
- Complication detection in MRI guided cardiac ablation: Atrial wall damage and hepatic oedema.Radiology case reports · 2024Article
- Cardiac MRI at Low Field Strengths.Journal of magnetic resonance imaging : JMRI · 2024Review
- Cardiac magnetic resonance haemodynamics in paediatric heart transplant patients: fick oximetry versus cardiac magnetic resonance phase contrast.Cardiology in the young · 2024Article
- Accuracy of free-breathing multi-parametric SASHA in identifying T1 and T2 elevations in pediatric orthotopic heart transplant patients.The international journal of cardiovascular imaging · 2024Article
- Evaluation of MR-safe bioptomes for MR-guided endomyocardial biopsy in minipigs: a potential radiation-free clinical approach.European radiology experimental · 2023Article
- Interventional cardiovascular magnetic resonance: state-of-the-art.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Review
- RF-induced heating of interventional devices at 23.66 MHz.Magma (New York, N.Y.) · 2023Article
- MRI-Guided Cardiac Catheterization in Congenital Heart Disease: How to Get Started.Current cardiology reports · 2022Review
- Real-time CMR guidance for intracardiac and great vessel pressure mapping in patients with congenital heart disease using an MR conditional guidewire-results of 25 patients.Cardiovascular diagnosis and therapy · 2021Article
- Micro-biopsy for detection of gene expression changes in ischemic swine myocardium: A pilot study.PloS one · 2021Article
- The Future of Paediatric Heart Interventions: Where Will We Be in 2030?Current cardiology reports · 2020Review
- Features and clinical impact of extra-cardiac lesions withInternational journal of cardiology. Heart & vasculature · 2020Article
- MRI Catheterization: Ready for Broad Adoption.Pediatric cardiology · 2020Review
- Introduction of a CMR-conditional cardiac phantom simulating cardiac anatomy and function and enabling training of interventional CMR procedures.Scientific reports · 2019Article
- 3D Myocardial Scar Prediction Model Derived from Multimodality Analysis of Electromechanical Mapping and Magnetic Resonance Imaging.Journal of cardiovascular translational research · 2019Article
- CMR-guidance of passively tracked endomyocardial biopsy in an in vivo porcine model.The international journal of cardiovascular imaging · 2018Article
- Conduction Dysfunction and Near Expunction: Giant Cell Myocarditis.The American journal of medicine · 2018Article
- Real-time MRI guidance of cardiac interventions.Journal of magnetic resonance imaging : JMRI · 2017Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundDiagnostic yield of endomyocardial biopsy is low, particularly in disease that affects the myocardium in a non-uniform distribution. We hypothesized that real-time MRI guidance could improve the yield through targeted biopsy of focal myocardial pathology.
methodsAn animal model of focal myocardial pathology was created by infusing 3mL of fluorescent microspheres (NuFlow Hydrocoat, 15μm diameter, 5 million spheres/mL) followed by 2mL of 100% ethanol to a branch coronary artery. Animals were survived for minimum 14days, before undergoing MRI guided endomyocardial biopsy using a custom 6.5Fr active visualization MRI-conditional bioptome and X-ray guided biopsy using a commercial bioptome. Specimens were analyzed using a dissecting microscope under ultraviolet light to determine the proportion of 'on-target' specimens containing fluorescent microspheres.
resultsA total of 77 specimens were obtained using real-time MRI guidance and 87 using X-ray guidance, in five animals. Specimens obtained with the MRI-conditional bioptome were smaller compared with the commercial X-ray bioptome. Real-time MRI guidance significantly increased the diagnostic yield of endomyocardial biopsy (82% vs. 56% on-target biopsy specimens with real-time MRI vs. X-ray guidance, p<0.01).
conclusionsEndomyocardial biopsy performed using real-time MRI guidance is feasible and significantly improves the diagnostic yield compared with X-ray fluoroscopy guidance.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.